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Proteomic Profiling of Urinary Large Extracellular Vesicles for the Diagnosis of Prostate Cancer.

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Title: Proteomic Profiling of Urinary Large Extracellular Vesicles for the Diagnosis of Prostate Cancer.
Authors: Fan YP; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Zhang YT; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Zhang G; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, China., Ma L; Shanghai JINCE Clinical Laboratories, Shanghai 201101, China., Lv Y; School of Public Health, Wannan Medical College, Wuhu 241002, China., Li J; Central Laboratory of the First Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin 150081, China., Luan Y; EVLiXiR Biotech, Nanjing 210032, China., Zhang YX; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Chen YT; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Ren HY; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Liu W; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Li MH; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Wu YX; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China., Chen S; Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing 210009, China., Han B; Department of Pharmacology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing 210009, China., Tang QY; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China., Chen LH; Xiamen Xianyue Hospital, Xiamen 361012, China., Wesselius A; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.; School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht 6229ER, The Netherlands., Su WC; Xiamen Xianyue Hospital, Xiamen 361012, China., Zeegers MP; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.; School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht 6229ER, The Netherlands., Gu Y; Department of Oncology and Cancer Rehabilitation Centre, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Qin QR; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, China.; Ma'anshan Center for Disease Control and Prevention, Ma'anshan 243011, China., Hao H; Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210002, China., Xia J; Department of Chemistry, the Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China., Zhang H; Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210002, China., Yu EY; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.
Source: Analytical chemistry [Anal Chem] 2025 Aug 19; Vol. 97 (32), pp. 17368-17379. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
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  Data: Proteomic Profiling of Urinary Large Extracellular Vesicles for the Diagnosis of Prostate Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Fan+YP%22">Fan YP</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YT%22">Zhang YT</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Shanghai JINCE Clinical Laboratories, Shanghai 201101, China.<br /><searchLink fieldCode="AU" term="%22Lv+Y%22">Lv Y</searchLink>; School of Public Health, Wannan Medical College, Wuhu 241002, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Central Laboratory of the First Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin 150081, China.<br /><searchLink fieldCode="AU" term="%22Luan+Y%22">Luan Y</searchLink>; EVLiXiR Biotech, Nanjing 210032, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YX%22">Zhang YX</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Chen+YT%22">Chen YT</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Ren+HY%22">Ren HY</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Liu+W%22">Liu W</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Li+MH%22">Li MH</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Wu+YX%22">Wu YX</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Han+B%22">Han B</searchLink>; Department of Pharmacology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing 210009, China.<br /><searchLink fieldCode="AU" term="%22Tang+QY%22">Tang QY</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.<br /><searchLink fieldCode="AU" term="%22Chen+LH%22">Chen LH</searchLink>; Xiamen Xianyue Hospital, Xiamen 361012, China.<br /><searchLink fieldCode="AU" term="%22Wesselius+A%22">Wesselius A</searchLink>; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.; School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht 6229ER, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Su+WC%22">Su WC</searchLink>; Xiamen Xianyue Hospital, Xiamen 361012, China.<br /><searchLink fieldCode="AU" term="%22Zeegers+MP%22">Zeegers MP</searchLink>; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.; School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht 6229ER, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Department of Oncology and Cancer Rehabilitation Centre, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.<br /><searchLink fieldCode="AU" term="%22Qin+QR%22">Qin QR</searchLink>; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210009, China.; Ma'anshan Center for Disease Control and Prevention, Ma'anshan 243011, China.<br /><searchLink fieldCode="AU" term="%22Hao+H%22">Hao H</searchLink>; Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210002, China.<br /><searchLink fieldCode="AU" term="%22Xia+J%22">Xia J</searchLink>; Department of Chemistry, the Chinese University of Hong Kong, Shatin, Hong Kong SAR 999077, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Critical Care Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210002, China.<br /><searchLink fieldCode="AU" term="%22Yu+EY%22">Yu EY</searchLink>; Department of Epidemiology & Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China.; Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht 6229ER, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%220370536%22">Analytical chemistry</searchLink> [Anal Chem] 2025 Aug 19; Vol. 97 (32), pp. 17368-17379. <i>Date of Electronic Publication: </i>2025 Jul 16.
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