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Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population.

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Title: Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population.
Authors: Wu TS; Department of Biomedical Sciences, Chung Shan Medical University, Taichung, 40201, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan.; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan., Chen YJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan., Hsiung CN; Data Science Statistical Cooperation Center, Institute of Statistical Science, Academia Sinica, Taipei, 11529, Taiwan., Mao CL; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan., Wei CY; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan., Chen IC; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan., Kao CM; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; Division of Translational Medicine, Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan., Hsiao TH; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan., Huang WN; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan., Chen YH; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan., Chen YM; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan. ymchen1@vghtc.gov.tw.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan. ymchen1@vghtc.gov.tw.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan. ymchen1@vghtc.gov.tw.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan. ymchen1@vghtc.gov.tw.; Graduate Institute of Clinical Medicine, College of Medicine, National Chung Hsing University, Taichung, 402202, Taiwan. ymchen1@vghtc.gov.tw.; Precision Medicine Research Center, College of Medicine, National Chung Hsing University, Taichung, 402202, Taiwan. ymchen1@vghtc.gov.tw.
Source: Scientific reports [Sci Rep] 2025 Jul 16; Vol. 15 (1), pp. 25700. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population.
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  Data: <searchLink fieldCode="AU" term="%22Wu+TS%22">Wu TS</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung, 40201, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan.; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YJ%22">Chen YJ</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsiung+CN%22">Hsiung CN</searchLink>; Data Science Statistical Cooperation Center, Institute of Statistical Science, Academia Sinica, Taipei, 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Mao+CL%22">Mao CL</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wei+CY%22">Wei CY</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IC%22">Chen IC</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kao+CM%22">Kao CM</searchLink>; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; Division of Translational Medicine, Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsiao+TH%22">Hsiao TH</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+WN%22">Huang WN</searchLink>; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YM%22">Chen YM</searchLink>; Department of Medical Research, Taichung Veterans General Hospital, Taichung, 40705, Taiwan. ymchen1@vghtc.gov.tw.; Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, 1650, Section 4, Taiwan Boulevard, Xitun Dist, Taichung City, 40705, Taiwan. ymchen1@vghtc.gov.tw.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, 11221, Taiwan. ymchen1@vghtc.gov.tw.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan. ymchen1@vghtc.gov.tw.; Graduate Institute of Clinical Medicine, College of Medicine, National Chung Hsing University, Taichung, 402202, Taiwan. ymchen1@vghtc.gov.tw.; Precision Medicine Research Center, College of Medicine, National Chung Hsing University, Taichung, 402202, Taiwan. ymchen1@vghtc.gov.tw.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Jul 16; Vol. 15 (1), pp. 25700. <i>Date of Electronic Publication: </i>2025 Jul 16.
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        Value: 10.1038/s41598-025-08254-1
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              Text: 2025 Jul 16
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