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Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.

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Title: Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
Authors: Hsu WT; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan. wantsenghsu@ntu.edu.tw., Kobuchi S; Laboratory of Pharmacokinetics, Kyoto Pharmaceutical University, Kyoto, Japan., Chien TR; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan., Chen IC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan., Hamada S; Division of Pharmaceutical Sciences, Kanazawa University, Kanazawa, Japan., Tsujimoto M; Laboratory of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan., Tsai IL; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Wong YS; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan., Tung KH; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan., He YZ; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan.
Source: Biology direct [Biol Direct] 2025 Jul 16; Vol. 20 (1), pp. 84. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
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  Data: <searchLink fieldCode="AU" term="%22Hsu+WT%22">Hsu WT</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan. wantsenghsu@ntu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Kobuchi+S%22">Kobuchi S</searchLink>; Laboratory of Pharmacokinetics, Kyoto Pharmaceutical University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Chien+TR%22">Chien TR</searchLink>; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IC%22">Chen IC</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hamada+S%22">Hamada S</searchLink>; Division of Pharmaceutical Sciences, Kanazawa University, Kanazawa, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujimoto+M%22">Tsujimoto M</searchLink>; Laboratory of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Tsai+IL%22">Tsai IL</searchLink>; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wong+YS%22">Wong YS</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tung+KH%22">Tung KH</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan.<br /><searchLink fieldCode="AU" term="%22He+YZ%22">He YZ</searchLink>; School of Pharmacy, College of Medicine, National Taiwan University, 33 Linsen S. Rd., R201, Zhongzheng Dist, Taipei, 100025, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101258412%22">Biology direct</searchLink> [Biol Direct] 2025 Jul 16; Vol. 20 (1), pp. 84. <i>Date of Electronic Publication: </i>2025 Jul 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101258412 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6150 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456150%22">17456150 </searchLink><i>NLM ISO Abbreviation: </i>Biol Direct <i>Subsets: </i>MEDLINE
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              Text: 2025 Jul 16
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