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Controlled colonization of the human gut with a genetically engineered microbial therapeutic.

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Title: Controlled colonization of the human gut with a genetically engineered microbial therapeutic.
Authors: Whitaker WR; Novome Biotechnologies, South San Francisco, CA, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Russ ZN; Novome Biotechnologies, South San Francisco, CA, USA., Stanley Shepherd E; Novome Biotechnologies, South San Francisco, CA, USA., Popov LM; Novome Biotechnologies, South San Francisco, CA, USA., Louie A; Novome Biotechnologies, South San Francisco, CA, USA., Lam K; Novome Biotechnologies, South San Francisco, CA, USA., Zong DM; Novome Biotechnologies, South San Francisco, CA, USA., Gill CCC; Novome Biotechnologies, South San Francisco, CA, USA., Gehrig JL; Novome Biotechnologies, South San Francisco, CA, USA., Rishi HS; Novome Biotechnologies, South San Francisco, CA, USA., Tan JA; Novome Biotechnologies, South San Francisco, CA, USA., Buness A; Novome Biotechnologies, South San Francisco, CA, USA., Godoy J; Novome Biotechnologies, South San Francisco, CA, USA., Banta D; Novome Biotechnologies, South San Francisco, CA, USA., Jaidka S; Novome Biotechnologies, South San Francisco, CA, USA., Wilson K; Novome Biotechnologies, South San Francisco, CA, USA., Flood J; Novome Biotechnologies, South San Francisco, CA, USA., Bukshpun P; Novome Biotechnologies, South San Francisco, CA, USA., Yocum R; Novome Biotechnologies, South San Francisco, CA, USA., Cook DN; Novome Biotechnologies, South San Francisco, CA, USA., Warsi T; Novome Biotechnologies, South San Francisco, CA, USA., McLean L; Novome Biotechnologies, South San Francisco, CA, USA., Sonnenburg JL; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Center for Human Microbiome Studies, Stanford University School of Medicine, Stanford, CA, USA., DeLoache WC; Novome Biotechnologies, South San Francisco, CA, USA.
Source: Science (New York, N.Y.) [Science] 2025 Jul 17; Vol. 389 (6757), pp. 303-308. Date of Electronic Publication: 2025 Jul 17.
Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Controlled colonization of the human gut with a genetically engineered microbial therapeutic.
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  Data: <searchLink fieldCode="AU" term="%22Whitaker+WR%22">Whitaker WR</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Russ+ZN%22">Russ ZN</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stanley+Shepherd+E%22">Stanley Shepherd E</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Popov+LM%22">Popov LM</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Louie+A%22">Louie A</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lam+K%22">Lam K</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zong+DM%22">Zong DM</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gill+CCC%22">Gill CCC</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gehrig+JL%22">Gehrig JL</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rishi+HS%22">Rishi HS</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tan+JA%22">Tan JA</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Buness+A%22">Buness A</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Godoy+J%22">Godoy J</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Banta+D%22">Banta D</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jaidka+S%22">Jaidka S</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+K%22">Wilson K</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Flood+J%22">Flood J</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bukshpun+P%22">Bukshpun P</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yocum+R%22">Yocum R</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+DN%22">Cook DN</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Warsi+T%22">Warsi T</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22McLean+L%22">McLean L</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sonnenburg+JL%22">Sonnenburg JL</searchLink>; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Center for Human Microbiome Studies, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22DeLoache+WC%22">DeLoache WC</searchLink>; Novome Biotechnologies, South San Francisco, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2025 Jul 17; Vol. 389 (6757), pp. 303-308. <i>Date of Electronic Publication: </i>2025 Jul 17.
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  Data: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0404511 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200368075%22">00368075 </searchLink><i>NLM ISO Abbreviation: </i>Science <i>Subsets: </i>MEDLINE
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              Text: 2025 Jul 17
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