Potent Acridone Antimalarial against All Three Life Stages of Plasmodium.
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| Title: | Potent Acridone Antimalarial against All Three Life Stages of Plasmodium. |
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| Authors: | Kancharla P; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States., Dodean RA; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States., Li Y; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States., Zhang X; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States., Kelly S; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States., Charlton J; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States., Binauhan A; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States., Garcia L; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States., Caridha D; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Madejczyk MS; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Jin X; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Dennis WE; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Kudyba K; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., McEnearney S; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Lee PJ; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Blount C; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., DeLuca J; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Vuong C; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Pannone K; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Dinh HT; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Mdaki K; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Leed S; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Martin ML; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Pybus BS; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States., Chimong A; Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States., Cui L; Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States., Vega-Rodriguez J; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, Maryland 20852, United States., Okitwi M; Infectious Diseases Research Collaboration, Kampala, Uganda., Kreutzfeld O; Department of Medicine, University of California San Francisco, San Francisco, California 94143, United States., Docan C; SRI International, Biosciences Division, Menlo Park, California 94025, United States., Green C; SRI International, Biosciences Division, Menlo Park, California 94025, United States., Liu Y; SRI International, Biosciences Division, Menlo Park, California 94025, United States., Agulay A; SRI International, Biosciences Division, Menlo Park, California 94025, United States., Mirsalis J; SRI International, Biosciences Division, Menlo Park, California 94025, United States., Farrell SN; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia., McFadden GI; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia., Goodman CD; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia., Probst AS; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, 02115, United States., Nilsen A; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.; Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon 97239, United States., Catteruccia F; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, 02115, United States.; Howard Hughes Medical Institute, Boston, Massachusetts, 02115, United States., Rosenthal PJ; Department of Medicine, University of California San Francisco, San Francisco, California 94143, United States., Riscoe M; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.; Microbiology and Molecular Immunology, Oregon Health & Science University, Portland, Oregon 97239, United States., Cooper R; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States., Roth A; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States., Kelly J; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States. |
| Source: | Research square [Res Sq] 2025 Jun 27. Date of Electronic Publication: 2025 Jun 27. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40678217 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Potent Acridone Antimalarial against All Three Life Stages of Plasmodium. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kancharla+P%22">Kancharla P</searchLink>; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.<br /><searchLink fieldCode="AU" term="%22Dodean+RA%22">Dodean RA</searchLink>; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Kelly+S%22">Kelly S</searchLink>; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Charlton+J%22">Charlton J</searchLink>; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.<br /><searchLink fieldCode="AU" term="%22Binauhan+A%22">Binauhan A</searchLink>; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.<br /><searchLink fieldCode="AU" term="%22Garcia+L%22">Garcia L</searchLink>; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.<br /><searchLink fieldCode="AU" term="%22Caridha+D%22">Caridha D</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Madejczyk+MS%22">Madejczyk MS</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Dennis+WE%22">Dennis WE</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Kudyba+K%22">Kudyba K</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22McEnearney+S%22">McEnearney S</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Lee+PJ%22">Lee PJ</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Blount+C%22">Blount C</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22DeLuca+J%22">DeLuca J</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Vuong+C%22">Vuong C</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Pannone+K%22">Pannone K</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Dinh+HT%22">Dinh HT</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Mdaki+K%22">Mdaki K</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Leed+S%22">Leed S</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Martin+ML%22">Martin ML</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Pybus+BS%22">Pybus BS</searchLink>; Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.<br /><searchLink fieldCode="AU" term="%22Chimong+A%22">Chimong A</searchLink>; Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.<br /><searchLink fieldCode="AU" term="%22Cui+L%22">Cui L</searchLink>; Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.<br /><searchLink fieldCode="AU" term="%22Vega-Rodriguez+J%22">Vega-Rodriguez J</searchLink>; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, Maryland 20852, United States.<br /><searchLink fieldCode="AU" term="%22Okitwi+M%22">Okitwi M</searchLink>; Infectious Diseases Research Collaboration, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kreutzfeld+O%22">Kreutzfeld O</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, California 94143, United States.<br /><searchLink fieldCode="AU" term="%22Docan+C%22">Docan C</searchLink>; SRI International, Biosciences Division, Menlo Park, California 94025, United States.<br /><searchLink fieldCode="AU" term="%22Green+C%22">Green C</searchLink>; SRI International, Biosciences Division, Menlo Park, California 94025, United States.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; SRI International, Biosciences Division, Menlo Park, California 94025, United States.<br /><searchLink fieldCode="AU" term="%22Agulay+A%22">Agulay A</searchLink>; SRI International, Biosciences Division, Menlo Park, California 94025, United States.<br /><searchLink fieldCode="AU" term="%22Mirsalis+J%22">Mirsalis J</searchLink>; SRI International, Biosciences Division, Menlo Park, California 94025, United States.<br /><searchLink fieldCode="AU" term="%22Farrell+SN%22">Farrell SN</searchLink>; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22McFadden+GI%22">McFadden GI</searchLink>; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Goodman+CD%22">Goodman CD</searchLink>; School of Biosciences, The University of Melbourne, Parkville, VIC, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Probst+AS%22">Probst AS</searchLink>; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, 02115, United States.<br /><searchLink fieldCode="AU" term="%22Nilsen+A%22">Nilsen A</searchLink>; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.; Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Catteruccia+F%22">Catteruccia F</searchLink>; Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, Massachusetts, 02115, United States.; Howard Hughes Medical Institute, Boston, Massachusetts, 02115, United States.<br /><searchLink fieldCode="AU" term="%22Rosenthal+PJ%22">Rosenthal PJ</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, California 94143, United States.<br /><searchLink fieldCode="AU" term="%22Riscoe+M%22">Riscoe M</searchLink>; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.; Microbiology and Molecular Immunology, Oregon Health & Science University, Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Cooper+R%22">Cooper R</searchLink>; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.<br /><searchLink fieldCode="AU" term="%22Roth+A%22">Roth A</searchLink>; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.<br /><searchLink fieldCode="AU" term="%22Kelly+J%22">Kelly J</searchLink>; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101768035%22">Research square</searchLink> [Res Sq] 2025 Jun 27. <i>Date of Electronic Publication: </i>2025 Jun 27. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101768035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2693-5015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226935015%22">26935015 </searchLink><i>NLM ISO Abbreviation: </i>Res Sq <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40678217 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.21203/rs.3.rs-6858328/v1 Languages: – Code: eng Text: English Titles: – TitleFull: Potent Acridone Antimalarial against All Three Life Stages of Plasmodium. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kancharla P – PersonEntity: Name: NameFull: Dodean RA – PersonEntity: Name: NameFull: Li Y – PersonEntity: Name: NameFull: Zhang X – PersonEntity: Name: NameFull: Kelly S – PersonEntity: Name: NameFull: Charlton J – PersonEntity: Name: NameFull: Binauhan A – PersonEntity: Name: NameFull: Garcia L – PersonEntity: Name: NameFull: Caridha D – PersonEntity: Name: NameFull: Madejczyk MS – PersonEntity: Name: NameFull: Jin X – PersonEntity: Name: NameFull: Dennis WE – PersonEntity: Name: NameFull: Kudyba K – PersonEntity: Name: NameFull: McEnearney S – PersonEntity: Name: NameFull: Lee PJ – PersonEntity: Name: NameFull: Blount C – PersonEntity: Name: NameFull: DeLuca J – PersonEntity: Name: NameFull: Vuong C – PersonEntity: Name: NameFull: Pannone K – PersonEntity: Name: NameFull: Dinh HT – PersonEntity: Name: NameFull: Mdaki K – PersonEntity: Name: NameFull: Leed S – PersonEntity: Name: NameFull: Martin ML – PersonEntity: Name: NameFull: Pybus BS – PersonEntity: Name: NameFull: Chimong A – PersonEntity: Name: NameFull: Cui L – PersonEntity: Name: NameFull: Vega-Rodriguez J – PersonEntity: Name: NameFull: Okitwi M – PersonEntity: Name: NameFull: Kreutzfeld O – PersonEntity: Name: NameFull: Docan C – PersonEntity: Name: NameFull: Green C – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Agulay A – PersonEntity: Name: NameFull: Mirsalis J – PersonEntity: Name: NameFull: Farrell SN – PersonEntity: Name: NameFull: McFadden GI – PersonEntity: Name: NameFull: Goodman CD – PersonEntity: Name: NameFull: Probst AS – PersonEntity: Name: NameFull: Nilsen A – PersonEntity: Name: NameFull: Catteruccia F – PersonEntity: Name: NameFull: Rosenthal PJ – PersonEntity: Name: NameFull: Riscoe M – PersonEntity: Name: NameFull: Cooper R – PersonEntity: Name: NameFull: Roth A – PersonEntity: Name: NameFull: Kelly J IsPartOfRelationships: – BibEntity: Dates: – D: 27 M: 06 Text: 2025 Jun 27 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2693-5015 Titles: – TitleFull: Research square Type: main |
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