Iodine-promoted oxidative cross-coupling for the synthesis of (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)-3-phenylquinazolin-4(3H)-one via C-H activation: development of synthetic TLX agonists.
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| Title: | Iodine-promoted oxidative cross-coupling for the synthesis of (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)-3-phenylquinazolin-4(3H)-one via C-H activation: development of synthetic TLX agonists. |
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| Authors: | Maram L; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA. belgendy@wustl.edu.; Center for Clinical Pharmacology, Washington University School of Medicine and University of Health Sciences and Pharmacy, St Louis, MO 63110, USA.; Department of Pharmaceutical and Administrative Sciences, University of Health Sciences and Pharmacy, St Louis, MO 63110, USA., Zhao P; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA. belgendy@wustl.edu.; Center for Clinical Pharmacology, Washington University School of Medicine and University of Health Sciences and Pharmacy, St Louis, MO 63110, USA.; Department of Pharmaceutical and Administrative Sciences, University of Health Sciences and Pharmacy, St Louis, MO 63110, USA., Koelblen T; University of Florida Genetics Institute, University of Florida School of Medicine, Gainesville, FL, USA.; University of Florida College of Pharmacy, Department of Cellular and Systems Pharmacology, Gainesville, FL, USA., Hegazy L; Center for Clinical Pharmacology, Washington University School of Medicine and University of Health Sciences and Pharmacy, St Louis, MO 63110, USA.; Department of Pharmaceutical and Administrative Sciences, University of Health Sciences and Pharmacy, St Louis, MO 63110, USA., Burris TP; University of Florida Genetics Institute, University of Florida School of Medicine, Gainesville, FL, USA.; University of Florida College of Pharmacy, Department of Cellular and Systems Pharmacology, Gainesville, FL, USA., Elgendy B; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA. belgendy@wustl.edu.; Center for Clinical Pharmacology, Washington University School of Medicine and University of Health Sciences and Pharmacy, St Louis, MO 63110, USA.; Department of Pharmaceutical and Administrative Sciences, University of Health Sciences and Pharmacy, St Louis, MO 63110, USA. |
| Source: | Organic & biomolecular chemistry [Org Biomol Chem] 2025 Aug 06; Vol. 23 (31), pp. 7298-7313. Date of Electronic Publication: 2025 Aug 06. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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