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Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer.

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Title: Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer.
Authors: Delfinis LJ; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: delfinis@yorku.ca., Khajehzadehshoushtar S; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: sshoush@yorku.ca., Flewwelling LD; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: lukedf@yorku.ca., Andrews NJ; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: joela9@yorku.ca., Garibotti MC; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: mgarib@yorku.ca., Gandhi S; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: shivamg@yorku.ca., Brahmbhatt AN; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: anbrahm4@yorku.ca., Morris BA; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: brookeam@yorku.ca., Garlisi B; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: bgarlisi@uoguelph.ca., Lauks S; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: slauks@uoguelph.ca., Aitken C; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: caitke01@uoguelph.ca., Ogilvie L; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: ogilviel@uoguelph.ca., Tsitkanou S; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, 71656, USA. Electronic address: st060@uark.edu., Simpson JA; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: jeremys@uoguelph.ca., Greene NP; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, 71656, USA. Electronic address: npgreene@uark.edu., Cheng AJ; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: ajcheng@yorku.ca., Petrik J; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: jpetrik@uoguelph.ca., Perry CGR; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: cperry@yorku.ca.
Source: Molecular metabolism [Mol Metab] 2025 Sep; Vol. 99, pp. 102211. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE
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  Data: Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Delfinis+LJ%22">Delfinis LJ</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: delfinis@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Khajehzadehshoushtar+S%22">Khajehzadehshoushtar S</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: sshoush@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Flewwelling+LD%22">Flewwelling LD</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: lukedf@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Andrews+NJ%22">Andrews NJ</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: joela9@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Garibotti+MC%22">Garibotti MC</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: mgarib@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Gandhi+S%22">Gandhi S</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: shivamg@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Brahmbhatt+AN%22">Brahmbhatt AN</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: anbrahm4@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Morris+BA%22">Morris BA</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: brookeam@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Garlisi+B%22">Garlisi B</searchLink>; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: bgarlisi@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Lauks+S%22">Lauks S</searchLink>; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: slauks@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Aitken+C%22">Aitken C</searchLink>; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: caitke01@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Ogilvie+L%22">Ogilvie L</searchLink>; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: ogilviel@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Tsitkanou+S%22">Tsitkanou S</searchLink>; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, 71656, USA. Electronic address: st060@uark.edu.<br /><searchLink fieldCode="AU" term="%22Simpson+JA%22">Simpson JA</searchLink>; Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: jeremys@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Greene+NP%22">Greene NP</searchLink>; Cachexia Research Laboratory, Department of Health, Human Performance and Recreation, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, 71656, USA. Electronic address: npgreene@uark.edu.<br /><searchLink fieldCode="AU" term="%22Cheng+AJ%22">Cheng AJ</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: ajcheng@yorku.ca.<br /><searchLink fieldCode="AU" term="%22Petrik+J%22">Petrik J</searchLink>; Department of Biomedical Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: jpetrik@uoguelph.ca.<br /><searchLink fieldCode="AU" term="%22Perry+CGR%22">Perry CGR</searchLink>; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, ON, M3J 1P3, Canada. Electronic address: cperry@yorku.ca.
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  Data: <searchLink fieldCode="JN" term="%22101605730%22">Molecular metabolism</searchLink> [Mol Metab] 2025 Sep; Vol. 99, pp. 102211. <i>Date of Electronic Publication: </i>2025 Jul 16.
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