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Small Molecule Regulation of Iron Homeostasis: Design and Optimization of Novel Iron Chelators Based on a Thiosemicarbazone Scaffold.

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Title: Small Molecule Regulation of Iron Homeostasis: Design and Optimization of Novel Iron Chelators Based on a Thiosemicarbazone Scaffold.
Authors: Parry CS; Department of Microbiology, College of Medicine, Howard University, Washington, District of Columbia 20059. United States., Li Y; Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742. United States., Kwofie SK; Department of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra LG 77. Ghana., Valencia J; College of Natural and Mathematical Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250. United States., Tope Niedermaier CA; College of Natural and Mathematical Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250. United States., Ramadhar TR; Department of Chemistry, College of Arts and Science, Howard University, Washington, District of Columbia 20059. United States., Nekhai S; Center for Sickle Cell Disease, Department of Medicine, Howard University, Washington District of Columbia 20060. United States., Wilson MD; Department of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Legon, Accra LG 581. Ghana., Butcher RJ; Department of Chemistry, College of Arts and Science, Howard University, Washington, District of Columbia 20059. United States.
Source: Journal of molecular structure [J Mol Struct] 2025 Jul 05; Vol. 1334. Date of Electronic Publication: 2025 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0141747 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2860 (Print) Linking ISSN: 00222860 NLM ISO Abbreviation: J Mol Struct Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Parry+CS%22">Parry CS</searchLink>; Department of Microbiology, College of Medicine, Howard University, Washington, District of Columbia 20059. United States.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742. United States.<br /><searchLink fieldCode="AU" term="%22Kwofie+SK%22">Kwofie SK</searchLink>; Department of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Legon, Accra LG 77. Ghana.<br /><searchLink fieldCode="AU" term="%22Valencia+J%22">Valencia J</searchLink>; College of Natural and Mathematical Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250. United States.<br /><searchLink fieldCode="AU" term="%22Tope+Niedermaier+CA%22">Tope Niedermaier CA</searchLink>; College of Natural and Mathematical Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250. United States.<br /><searchLink fieldCode="AU" term="%22Ramadhar+TR%22">Ramadhar TR</searchLink>; Department of Chemistry, College of Arts and Science, Howard University, Washington, District of Columbia 20059. United States.<br /><searchLink fieldCode="AU" term="%22Nekhai+S%22">Nekhai S</searchLink>; Center for Sickle Cell Disease, Department of Medicine, Howard University, Washington District of Columbia 20060. United States.<br /><searchLink fieldCode="AU" term="%22Wilson+MD%22">Wilson MD</searchLink>; Department of Parasitology, Noguchi Memorial Institute for Medical Research (NMIMR), College of Health Sciences (CHS), University of Ghana, Legon, Accra LG 581. Ghana.<br /><searchLink fieldCode="AU" term="%22Butcher+RJ%22">Butcher RJ</searchLink>; Department of Chemistry, College of Arts and Science, Howard University, Washington, District of Columbia 20059. United States.
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        Value: 10.1016/j.molstruc.2025.141859
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        Text: English
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      – TitleFull: Small Molecule Regulation of Iron Homeostasis: Design and Optimization of Novel Iron Chelators Based on a Thiosemicarbazone Scaffold.
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              Text: 2025 Jul 05
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