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Machine learning in Alzheimer's disease genetics.

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Title: Machine learning in Alzheimer's disease genetics.
Authors: Bracher-Smith M; School of Medicine, Cardiff University, Cardiff, UK.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., Melograna F; BIO3 - Systems Medicine, Department of Human Genetics, KU Leuven, Leuven, Belgium.; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium., Ulm B; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom., Bellenguez C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France., Grenier-Boley B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France., Duroux D; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium., Nevado AJ; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom., Holmans P; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., Tijms BM; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands., Hulsman M; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands., de Rojas I; Research Center and Memory Clinic, ACE Alzheimer Center Barcelona. Universitat Internacional de Catalunya, Catalunya, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Campos-Martin R; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Estudios en Neurociencias y Sistemas Complejos (ENyS) CONICET-HEC-UNAJ, Buenos Aires, Argentina., der Lee SV; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands., Castillo A; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., Küçükali F; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Peters O; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Hindenburgdamm 30, 12203, Berlin, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany., Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Rujescu D; Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria., Scherbaum N; Department of Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Germany Medical Faculty, Essen, Germany., Deckert J; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germany., Riedel-Heller S; Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, 04103, Leipzig, Germany., Hausner L; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Molina-Porcel L; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, Fundació Recerca Clinic Barcelona- Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), and University of Barcelona, Barcelona, Spain.; Neurological Tissue Bank - Biobank, Hospital Clinic-FRCB-IDIBAPS, Barcelona, Spain., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Grimmer T; Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Medical Science Department, iBiMED, Aveiro, Portugal., Heilmann-Heimbach S; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Moebus S; Institute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany., Tegos T; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece., Scarmeas N; Taub Institute for Research in Alzheimer's Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York, NY, USA.; 1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Dols-Icardo O; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Moreno F; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Department of Neurology. Hospital Universitario Donostia, San Sebastian, Spain.; Neurosciences Area, Instituto Biogipuzkoa, San Sebastian, Spain., Pérez-Tur J; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain., Bullido MJ; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain.; Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.; Universidad Autónoma de Madrid, Madrid, Spain., Pastor P; Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Sánchez-Valle R; Alzheimer's disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain., Álvarez V; Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Asturias, Spain., Boada M; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., García-González P; Research Center and Memory clinic. ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Puerta R; Research Center and Memory clinic. ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain., Mir P; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain., Real LM; Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain., Piñol-Ripoll G; Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain., García-Alberca JM; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain.; Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain., Rodriguez-Rodriguez E; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Soininen H; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland., Heikkinen S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., de Mendonça A; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Mehrabian S; Clinic of Neurology, UH 'Alexandrovska', Medical University - Sofia, Sofia, Bulgaria., Traykov L; Department of Neurology, Medical University - Sofia, Sofia, Bulgaria., Hort J; Memory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Praha, Czech Republic., Vyhnalek M; Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Praha, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic., Sandau N; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Thomassen JQ; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Pijnenburg YAL; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands., Holstege H; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands., van Swieten J; Department of Neurology, ErasmusMC, Rotterdam, Netherlands., Ramakers I; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands., Verhey F; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands., Scheltens P; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands., Graff C; Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, 171 64, Stockholm, Sweden., Papenberg G; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Giedraitis V; Dept.of Public Health and Carins Sciences / Geriatrics, Uppsala University, Uppsala, Sweden., Williams J; School of Medicine, Cardiff University, Cardiff, UK.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., Amouyel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France., Boland A; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France., Deleuze JF; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France., Nicolas G; Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Genetics and CNRMAJ, F-, 76000, Rouen, France., Dufouil C; Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France.; CHU de Bordeaux, Pole santé publique, Bordeaux, France., Pasquier F; Univ Lille Inserm 1171, CHU Clinical and Research Memory Research Centre (CMRR) of Distalz Lille France, Lille, France., Hanon O; Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France., Debette S; University Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital, Bordeaux, France., Grünblatt E; Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland., Popp J; CHUV, Old Age Psychiatry, Department of Psychiatry, Lausanne, Switzerland.; Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.; Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich, Zürich, Switzerland., Ghidoni R; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Galimberti D; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, IT, Italy.; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, IT, Italy., Arosio B; Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy.; Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy., Mecocci P; Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Solfrizzi V; Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unit, University of Bari 'A. Moro', Bari, Italy., Parnetti L; Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy., Squassina A; Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy., Tremolizzo L; Neurology Unit, 'San Gerardo' hospital, Monza and University of Milano-Bicocca, Milan, Italy., Borroni B; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany., Nacmias B; Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy.; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Spallazzi M; Department of Medicine and Surgery, Unit of Neurology, University-Hospital of Parma, Parma, Italy., Seripa D; Department of Hematology and Stem Cell Transplant, Vito Fazzi Hospital, Lecce, Italy., Rainero I; Department of Neuroscience 'Rita Levi Montalcini', University of Torino, Torino, Italy., Daniele A; Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.; Neurology Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy., Piras F; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Masullo C; Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy., Rossi G; Unit of Neurology V - Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Jessen F; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany., Kehoe P; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Magda T; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece.; Laboratory of Genetics, Immunology and Human Pathology, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunis, Tunisia., Sánchez-Juan P; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII, 28031, Madrid, Spain., Sleegers K; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Ingelsson M; Dept. of Public Health and Caring Sciences / Geriatrics, Uppsala University, Uppsala, Sweden.; Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada., Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland., Sims R; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK., van der Flier W; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands., Andreassen OA; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Ruiz A; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.; Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA., Ramirez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany., Frikke-Schmidt R; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Amin N; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Roshchupkin G; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands., Lambert JC; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France., Van Steen K; BIO3 - Systems Medicine, Department of Human Genetics, KU Leuven, Leuven, Belgium. kristel.vansteen@uliege.be.; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium. kristel.vansteen@uliege.be., van Duijn C; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. cornelia.vanduijn@ndph.ox.ac.uk.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom. cornelia.vanduijn@ndph.ox.ac.uk.; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands. cornelia.vanduijn@ndph.ox.ac.uk., Escott-Price V; School of Medicine, Cardiff University, Cardiff, UK. EscottPriceV@cardiff.ac.uk.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK. EscottPriceV@cardiff.ac.uk.
Corporate Authors: EADB
Source: Nature communications [Nat Commun] 2025 Jul 22; Vol. 16 (1), pp. 6726. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Machine learning in Alzheimer's disease genetics.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Bracher-Smith+M%22">Bracher-Smith M</searchLink>; School of Medicine, Cardiff University, Cardiff, UK.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Melograna+F%22">Melograna F</searchLink>; BIO3 - Systems Medicine, Department of Human Genetics, KU Leuven, Leuven, Belgium.; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Ulm+B%22">Ulm B</searchLink>; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bellenguez+C%22">Bellenguez C</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Grenier-Boley+B%22">Grenier-Boley B</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Duroux+D%22">Duroux D</searchLink>; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Nevado+AJ%22">Nevado AJ</searchLink>; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Holmans+P%22">Holmans P</searchLink>; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Tijms+BM%22">Tijms BM</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hulsman+M%22">Hulsman M</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Rojas+I%22">de Rojas I</searchLink>; Research Center and Memory Clinic, ACE Alzheimer Center Barcelona. Universitat Internacional de Catalunya, Catalunya, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Campos-Martin+R%22">Campos-Martin R</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Estudios en Neurociencias y Sistemas Complejos (ENyS) CONICET-HEC-UNAJ, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22der+Lee+SV%22">der Lee SV</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Castillo+A%22">Castillo A</searchLink>; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Küçükali+F%22">Küçükali F</searchLink>; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Hindenburgdamm 30, 12203, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Dichgans+M%22">Dichgans M</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rujescu+D%22">Rujescu D</searchLink>; Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Scherbaum+N%22">Scherbaum N</searchLink>; Department of Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Germany Medical Faculty, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Deckert+J%22">Deckert J</searchLink>; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Riedel-Heller+S%22">Riedel-Heller S</searchLink>; Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, 04103, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Hausner+L%22">Hausner L</searchLink>; Department of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Molina-Porcel+L%22">Molina-Porcel L</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic of Barcelona, Fundació Recerca Clinic Barcelona- Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), and University of Barcelona, Barcelona, Spain.; Neurological Tissue Bank - Biobank, Hospital Clinic-FRCB-IDIBAPS, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Grimmer+T%22">Grimmer T</searchLink>; Center for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Medical Science Department, iBiMED, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Heilmann-Heimbach+S%22">Heilmann-Heimbach S</searchLink>; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Moebus+S%22">Moebus S</searchLink>; Institute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Tegos+T%22">Tegos T</searchLink>; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece.<br /><searchLink fieldCode="AU" term="%22Scarmeas+N%22">Scarmeas N</searchLink>; Taub Institute for Research in Alzheimer's Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York, NY, USA.; 1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Dols-Icardo+O%22">Dols-Icardo O</searchLink>; Sant Pau Memory Unit, Institut de Recerca Sant Pau, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Moreno+F%22">Moreno F</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Department of Neurology. Hospital Universitario Donostia, San Sebastian, Spain.; Neurosciences Area, Instituto Biogipuzkoa, San Sebastian, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Tur+J%22">Pérez-Tur J</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Unitat de Genètica Molecular, Institut de Biomedicina de València-CSIC, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bullido+MJ%22">Bullido MJ</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Centro de Biología Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain.; Instituto de Investigacion Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.; Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Pastor+P%22">Pastor P</searchLink>; Fundació Docència i Recerca MútuaTerrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Valle+R%22">Sánchez-Valle R</searchLink>; Alzheimer's disease and other cognitive disorders unit. Service of Neurology. Hospital Clínic of Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+V%22">Álvarez V</searchLink>; Laboratorio de Genética. Hospital Universitario Central de Asturias, Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Asturias, Spain.<br /><searchLink fieldCode="AU" term="%22Boada+M%22">Boada M</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-González+P%22">García-González P</searchLink>; Research Center and Memory clinic. ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Puerta+R%22">Puerta R</searchLink>; Research Center and Memory clinic. ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mir+P%22">Mir P</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Real+LM%22">Real LM</searchLink>; Unidad Clínica de Enfermedades Infecciosas y Microbiología. Hospital Universitario de Valme, Sevilla, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Piñol-Ripoll+G%22">Piñol-Ripoll G</searchLink>; Unitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.; Institut de Recerca Biomedica de Lleida (IRBLLeida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22García-Alberca+JM%22">García-Alberca JM</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Depatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga, Málaga, Spain.; Alzheimer Research Center & Memory Clinic, Andalusian Institute for Neuroscience, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Rodriguez+E%22">Rodriguez-Rodriguez E</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Soininen+H%22">Soininen H</searchLink>; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Heikkinen+S%22">Heikkinen S</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22de+Mendonça+A%22">de Mendonça A</searchLink>; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Mehrabian+S%22">Mehrabian S</searchLink>; Clinic of Neurology, UH 'Alexandrovska', Medical University - Sofia, Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Traykov+L%22">Traykov L</searchLink>; Department of Neurology, Medical University - Sofia, Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Hort+J%22">Hort J</searchLink>; Memory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Praha, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Vyhnalek+M%22">Vyhnalek M</searchLink>; Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Praha, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Sandau+N%22">Sandau N</searchLink>; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Thomassen+JQ%22">Thomassen JQ</searchLink>; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pijnenburg+YAL%22">Pijnenburg YAL</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Holstege+H%22">Holstege H</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Swieten+J%22">van Swieten J</searchLink>; Department of Neurology, ErasmusMC, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Ramakers+I%22">Ramakers I</searchLink>; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Verhey+F%22">Verhey F</searchLink>; Maastricht University, Department of Psychiatry & Neuropsychologie, Alzheimer Center Limburg, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Scheltens+P%22">Scheltens P</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Graff+C%22">Graff C</searchLink>; Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital-Solna, 171 64, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Papenberg+G%22">Papenberg G</searchLink>; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Giedraitis+V%22">Giedraitis V</searchLink>; Dept.of Public Health and Carins Sciences / Geriatrics, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Williams+J%22">Williams J</searchLink>; School of Medicine, Cardiff University, Cardiff, UK.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Amouyel+P%22">Amouyel P</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Boland+A%22">Boland A</searchLink>; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France.<br /><searchLink fieldCode="AU" term="%22Deleuze+JF%22">Deleuze JF</searchLink>; Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine, 91057, Evry, France.<br /><searchLink fieldCode="AU" term="%22Nicolas+G%22">Nicolas G</searchLink>; Univ Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Genetics and CNRMAJ, F-, 76000, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Dufouil+C%22">Dufouil C</searchLink>; Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, ISPED, CIC 1401-EC, Univ Bordeaux, Bordeaux, France.; CHU de Bordeaux, Pole santé publique, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Pasquier+F%22">Pasquier F</searchLink>; Univ Lille Inserm 1171, CHU Clinical and Research Memory Research Centre (CMRR) of Distalz Lille France, Lille, France.<br /><searchLink fieldCode="AU" term="%22Hanon+O%22">Hanon O</searchLink>; Université de Paris, EA 4468, APHP, Hôpital Broca, Paris, France.<br /><searchLink fieldCode="AU" term="%22Debette+S%22">Debette S</searchLink>; University Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Grünblatt+E%22">Grünblatt E</searchLink>; Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Popp+J%22">Popp J</searchLink>; CHUV, Old Age Psychiatry, Department of Psychiatry, Lausanne, Switzerland.; Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.; Department of Geriatric Psychiatry, University Hospital of Psychiatry Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ghidoni+R%22">Ghidoni R</searchLink>; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Galimberti+D%22">Galimberti D</searchLink>; Neurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, IT, Italy.; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, IT, Italy.<br /><searchLink fieldCode="AU" term="%22Arosio+B%22">Arosio B</searchLink>; Department of Clinical Sciences and Community Health, University of Milan, 20122, Milan, Italy.; Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mecocci+P%22">Mecocci P</searchLink>; Institute of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Solfrizzi+V%22">Solfrizzi V</searchLink>; Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unit, University of Bari 'A. Moro', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Parnetti+L%22">Parnetti L</searchLink>; Centre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Squassina+A%22">Squassina A</searchLink>; Department of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Tremolizzo+L%22">Tremolizzo L</searchLink>; Neurology Unit, 'San Gerardo' hospital, Monza and University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Borroni+B%22">Borroni B</searchLink>; Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Nacmias+B%22">Nacmias B</searchLink>; Department of Neuroscience, Psychology, Drug Research and Child Health University of Florence, Florence, Italy.; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Spallazzi+M%22">Spallazzi M</searchLink>; Department of Medicine and Surgery, Unit of Neurology, University-Hospital of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Seripa+D%22">Seripa D</searchLink>; Department of Hematology and Stem Cell Transplant, Vito Fazzi Hospital, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Rainero+I%22">Rainero I</searchLink>; Department of Neuroscience 'Rita Levi Montalcini', University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Daniele+A%22">Daniele A</searchLink>; Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.; Neurology Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Piras+F%22">Piras F</searchLink>; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Masullo+C%22">Masullo C</searchLink>; Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+G%22">Rossi G</searchLink>; Unit of Neurology V - Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kehoe+P%22">Kehoe P</searchLink>; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Magda+T%22">Magda T</searchLink>; 1st Department of Neurology, Medical school, Aristotle University of Thessaloniki, Thessaloniki, Makedonia, Greece.; Laboratory of Genetics, Immunology and Human Pathology, Faculty of Science of Tunis, University of Tunis El Manar, 2092, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Sánchez-Juan+P%22">Sánchez-Juan P</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII, 28031, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sleegers+K%22">Sleegers K</searchLink>; Complex Genetics of Alzheimer's Disease Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Ingelsson+M%22">Ingelsson M</searchLink>; Dept. of Public Health and Caring Sciences / Geriatrics, Uppsala University, Uppsala, Sweden.; Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, Departments of Medicine and Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hiltunen+M%22">Hiltunen M</searchLink>; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Sims+R%22">Sims R</searchLink>; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22van+der+Flier+W%22">van der Flier W</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Research Center and Memory clinic Fundació ACE, Institut Català de Neurociències Aplicades, Universitat Internacional de Catalunya, Barcelona, Spain.; Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez+A%22">Ramirez A</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Frikke-Schmidt+R%22">Frikke-Schmidt R</searchLink>; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Amin+N%22">Amin N</searchLink>; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Roshchupkin+G%22">Roshchupkin G</searchLink>; Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lambert+JC%22">Lambert JC</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.<br /><searchLink fieldCode="AU" term="%22Van+Steen+K%22">Van Steen K</searchLink>; BIO3 - Systems Medicine, Department of Human Genetics, KU Leuven, Leuven, Belgium. kristel.vansteen@uliege.be.; BIO3 - Systems Genetics, GIGA-R Molecular and Computational Biology, University of Liege, Liege, Belgium. kristel.vansteen@uliege.be.<br /><searchLink fieldCode="AU" term="%22van+Duijn+C%22">van Duijn C</searchLink>; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom. cornelia.vanduijn@ndph.ox.ac.uk.; Centre for Artificial Intelligence in Precision Medicine, University of Oxford, Oxford, United Kingdom. cornelia.vanduijn@ndph.ox.ac.uk.; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands. cornelia.vanduijn@ndph.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Escott-Price+V%22">Escott-Price V</searchLink>; School of Medicine, Cardiff University, Cardiff, UK. EscottPriceV@cardiff.ac.uk.; Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK. EscottPriceV@cardiff.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Jul 22; Vol. 16 (1), pp. 6726. <i>Date of Electronic Publication: </i>2025 Jul 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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      – TitleFull: Machine learning in Alzheimer's disease genetics.
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          Dates:
            – D: 22
              M: 07
              Text: 2025 Jul 22
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1