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High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study.

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Title: High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study.
Authors: Koo J; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Cooper R; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Edwards SL; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Lane A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Loveless SK; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Strecker L; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Lake KE; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Myers KC; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Towe C; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Patti J; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Walkup LL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA., Wikenheiser-Brokamp KA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., MacMillan ML; Pediatrics, Blood and Marrow Transplantation & Cellular Therapy Program, University of Minnesota, Minneapolis, Minnesota, USA., Lacher P; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA., Griffin T; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA., Tekman M; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA., Cisneros GS; Division of Pediatric Allergy, Immunology, and Blood and Marrow Transplantation, UCSF Benioff Children's Hospital, San Francisco, California, USA., Wu K; Division of Pediatric Allergy, Immunology, and Blood and Marrow Transplantation, UCSF Benioff Children's Hospital, San Francisco, California, USA., Zinter MS; Pediatric Critical Care Medicine, UCSF Benioff Children's Hospitals, San Francisco, California, USA., Urrego FA; Division of Pulmonary Medicine, University of California San Francisco, San Francisco, California, USA., Baker KS; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, Division of Hematology, Oncology, Blood and Marrow Transplantation, Seattle Children's Hospital, Seattle, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA., Abts MF; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, Washington, USA., Ballard S; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA., Freedman JL; Cellular Therapy and Transplant Section, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA., Caraballo A; Cellular Therapy and Transplant Section, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Young LR; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Josephson MB; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Allen JL; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Camburn DM; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Doherty EE; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA., Azamian MS; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA., Arredondo M; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA., Silva-Carmona M; Division of Pediatric Pulmonology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA., Lehmann LE; Center for Stem Cell Transplantation, Division of Hematologic Malignancy, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Wong W; Center for Stem Cell Transplantation, Division of Hematologic Malignancy, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Gaffin JM; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.; Division of Pulmonary and Sleep Medicine, Boston Children's Hospital, Boston, Massachusetts, USA., McAlpine W; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Li M; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Goldfarb SB; Division of Pediatric Pulmonary and Sleep Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Woods JC; Pediatrics, Blood and Marrow Transplantation & Cellular Therapy Program, University of Minnesota, Minneapolis, Minnesota, USA., Davies SM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2025 Oct; Vol. 72 (10), pp. e31916. Date of Electronic Publication: 2025 Jul 21.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study.
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  Data: <searchLink fieldCode="AU" term="%22Koo+J%22">Koo J</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Cooper+R%22">Cooper R</searchLink>; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+SL%22">Edwards SL</searchLink>; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Lane+A%22">Lane A</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Loveless+SK%22">Loveless SK</searchLink>; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Strecker+L%22">Strecker L</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Lake+KE%22">Lake KE</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Myers+KC%22">Myers KC</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Towe+C%22">Towe C</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Patti+J%22">Patti J</searchLink>; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Walkup+LL%22">Walkup LL</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Wikenheiser-Brokamp+KA%22">Wikenheiser-Brokamp KA</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.; Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22MacMillan+ML%22">MacMillan ML</searchLink>; Pediatrics, Blood and Marrow Transplantation & Cellular Therapy Program, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Lacher+P%22">Lacher P</searchLink>; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Griffin+T%22">Griffin T</searchLink>; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Tekman+M%22">Tekman M</searchLink>; Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Cisneros+GS%22">Cisneros GS</searchLink>; Division of Pediatric Allergy, Immunology, and Blood and Marrow Transplantation, UCSF Benioff Children's Hospital, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Wu+K%22">Wu K</searchLink>; Division of Pediatric Allergy, Immunology, and Blood and Marrow Transplantation, UCSF Benioff Children's Hospital, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Zinter+MS%22">Zinter MS</searchLink>; Pediatric Critical Care Medicine, UCSF Benioff Children's Hospitals, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Urrego+FA%22">Urrego FA</searchLink>; Division of Pulmonary Medicine, University of California San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Baker+KS%22">Baker KS</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, Division of Hematology, Oncology, Blood and Marrow Transplantation, Seattle Children's Hospital, Seattle, USA.; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Abts+MF%22">Abts MF</searchLink>; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.; Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Ballard+S%22">Ballard S</searchLink>; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Freedman+JL%22">Freedman JL</searchLink>; Cellular Therapy and Transplant Section, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Caraballo+A%22">Caraballo A</searchLink>; Cellular Therapy and Transplant Section, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Young+LR%22">Young LR</searchLink>; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Josephson+MB%22">Josephson MB</searchLink>; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Allen+JL%22">Allen JL</searchLink>; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania, Pennsylvania, USA.; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Camburn+DM%22">Camburn DM</searchLink>; Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Doherty+EE%22">Doherty EE</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Azamian+MS%22">Azamian MS</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Arredondo+M%22">Arredondo M</searchLink>; Baylor College of Medicine, Texas Children's Hospital, Center for Cell and Gene Therapy, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Silva-Carmona+M%22">Silva-Carmona M</searchLink>; Division of Pediatric Pulmonology, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Lehmann+LE%22">Lehmann LE</searchLink>; Center for Stem Cell Transplantation, Division of Hematologic Malignancy, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Wong+W%22">Wong W</searchLink>; Center for Stem Cell Transplantation, Division of Hematologic Malignancy, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gaffin+JM%22">Gaffin JM</searchLink>; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.; Division of Pulmonary and Sleep Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22McAlpine+W%22">McAlpine W</searchLink>; 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