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Duloxetine inhibits breast cancer progression by suppressing AKT signaling and inducing Bax/Bcl-2-mediated apoptosis.

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Title: Duloxetine inhibits breast cancer progression by suppressing AKT signaling and inducing Bax/Bcl-2-mediated apoptosis.
Authors: Wang J; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Yue Z; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Bu J; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Quan S; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Guo R; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Wang M; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Materia Medica, Henan University of Chinese Medicine, Zhengzhou, 450046, China., Shen J; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Shenjiduo@hactcm.edu.cn.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Shenjiduo@hactcm.edu.cn., Li M; Department of Oncology, Zhengzhou People's Hospital, Zhengzhou, 450003, China. Limin512_zz@126.com., Li Y; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Liyucheng@hactcm.edu.cn.; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Liyucheng@hactcm.edu.cn.
Source: Medical oncology (Northwood, London, England) [Med Oncol] 2025 Jul 22; Vol. 42 (8), pp. 364. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Duloxetine inhibits breast cancer progression by suppressing AKT signaling and inducing Bax/Bcl-2-mediated apoptosis.
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  Data: <searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Yue+Z%22">Yue Z</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Bu+J%22">Bu J</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Quan+S%22">Quan S</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Guo+R%22">Guo R</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China.; College of Materia Medica, Henan University of Chinese Medicine, Zhengzhou, 450046, China.<br /><searchLink fieldCode="AU" term="%22Shen+J%22">Shen J</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Shenjiduo@hactcm.edu.cn.; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Shenjiduo@hactcm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Oncology, Zhengzhou People's Hospital, Zhengzhou, 450003, China. Limin512_zz@126.com.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Collaborative Innovation Center of Research and Development on the Whole Industry Chain for Yu-Yao in Henan Province, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Liyucheng@hactcm.edu.cn.; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Liyucheng@hactcm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229435512%22">Medical oncology (Northwood, London, England)</searchLink> [Med Oncol] 2025 Jul 22; Vol. 42 (8), pp. 364. <i>Date of Electronic Publication: </i>2025 Jul 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9435512 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-131X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213570560%22">13570560 </searchLink><i>NLM ISO Abbreviation: </i>Med Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12032-025-02919-7
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              Text: 2025 Jul 22
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