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Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase.

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Title: Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase.
Authors: Lin CC; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology., Lin YT; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology., Chen SY; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology., Setayeshpour Y; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology., Chen Y; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology., Dunn DE; Department of Radiation Oncology, and., Nguyen T; Department of Radiation Oncology, and., Mestre AA; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.; Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina, USA., Banerjee A; School of Chemistry, University of Hyderabad, Hyderabad, India., Guruprasad L; School of Chemistry, University of Hyderabad, Hyderabad, India., Soderblom EJ; Proteomics and Metabolomics Core Facility., Zhang GF; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, and.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA., Lin CY; Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University, Washington, DC, USA., Filonenko V; Department of Cell Signaling, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine., Jeong SY; Department of Molecular & Medical Genetics., Floyd SR; Department of Radiation Oncology, and., Hayflick SJ; Department of Molecular & Medical Genetics.; Pediatrics, and Neurology, Oregon Health & Science University, Portland, Oregon, USA., Gout I; Department of Cell Signaling, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine.; Department of Structural and Molecular Biology, University College London, London, United Kingdom., Chi JT; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jul 22; Vol. 135 (19). Date of Electronic Publication: 2025 Jul 22 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase.
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  Data: <searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.<br /><searchLink fieldCode="AU" term="%22Lin+YT%22">Lin YT</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.<br /><searchLink fieldCode="AU" term="%22Chen+SY%22">Chen SY</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.<br /><searchLink fieldCode="AU" term="%22Setayeshpour+Y%22">Setayeshpour Y</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.<br /><searchLink fieldCode="AU" term="%22Dunn+DE%22">Dunn DE</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Nguyen+T%22">Nguyen T</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Mestre+AA%22">Mestre AA</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.; Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Banerjee+A%22">Banerjee A</searchLink>; School of Chemistry, University of Hyderabad, Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Guruprasad+L%22">Guruprasad L</searchLink>; School of Chemistry, University of Hyderabad, Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Soderblom+EJ%22">Soderblom EJ</searchLink>; Proteomics and Metabolomics Core Facility.<br /><searchLink fieldCode="AU" term="%22Zhang+GF%22">Zhang GF</searchLink>; Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, and.; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University School of Medicine, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Filonenko+V%22">Filonenko V</searchLink>; Department of Cell Signaling, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine.<br /><searchLink fieldCode="AU" term="%22Jeong+SY%22">Jeong SY</searchLink>; Department of Molecular & Medical Genetics.<br /><searchLink fieldCode="AU" term="%22Floyd+SR%22">Floyd SR</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Hayflick+SJ%22">Hayflick SJ</searchLink>; Department of Molecular & Medical Genetics.; Pediatrics, and Neurology, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Gout+I%22">Gout I</searchLink>; Department of Cell Signaling, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine.; Department of Structural and Molecular Biology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chi+JT%22">Chi JT</searchLink>; Department of Molecular Genetics and Microbiology.; Duke Center for Genomic and Computational Biology.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Jul 22; Vol. 135 (19). <i>Date of Electronic Publication: </i>2025 Jul 22 (<i>Print Publication: </i>2025).
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  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI190215
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        Text: English
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      – TitleFull: Coenzyme A protects against ferroptosis via CoAlation of mitochondrial thioredoxin reductase.
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              Text: 2025 Jul 22
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