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Predicting treatment-seeking status for alcohol use disorder using polygenic scores and machine learning in a deeply-phenotyped sample.

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Title: Predicting treatment-seeking status for alcohol use disorder using polygenic scores and machine learning in a deeply-phenotyped sample.
Authors: Jinwala Z; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States., Green R; Medical University of South Carolina, Charleston, SC 29425, United States., Khan Y; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States., Gelernter J; West Haven VA Medical Center, West Haven, CT 06516, United States; Yale University, New Haven, CT 06511, United States., Kember RL; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States., Hartwell EE; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address: Emily.hartwell@va.gov.
Source: Drug and alcohol dependence [Drug Alcohol Depend] 2025 Sep 01; Vol. 274, pp. 112797. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 7513587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0046 (Electronic) Linking ISSN: 03768716 NLM ISO Abbreviation: Drug Alcohol Depend Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Jinwala+Z%22">Jinwala Z</searchLink>; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.<br /><searchLink fieldCode="AU" term="%22Green+R%22">Green R</searchLink>; Medical University of South Carolina, Charleston, SC 29425, United States.<br /><searchLink fieldCode="AU" term="%22Khan+Y%22">Khan Y</searchLink>; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.<br /><searchLink fieldCode="AU" term="%22Gelernter+J%22">Gelernter J</searchLink>; West Haven VA Medical Center, West Haven, CT 06516, United States; Yale University, New Haven, CT 06511, United States.<br /><searchLink fieldCode="AU" term="%22Kember+RL%22">Kember RL</searchLink>; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.<br /><searchLink fieldCode="AU" term="%22Hartwell+EE%22">Hartwell EE</searchLink>; Crescenz VA Medical Center, Philadelphia, PA 19104, United States; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address: Emily.hartwell@va.gov.
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