Prevalence and outcomes of a pilot definition of severe refractory systemic lupus erythematosus: observations from a multinational Asia-Pacific cohort.

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Title: Prevalence and outcomes of a pilot definition of severe refractory systemic lupus erythematosus: observations from a multinational Asia-Pacific cohort.
Authors: Kandane-Rathnayake R; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia. rangi.kandane-rathnayake@monash.edu., Louthrenoo W; Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Lau CS; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong., Hamijoyo L; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia., Cho J; Rheumatology Division, Department of Medicine, National University Hospital, Singapore, Singapore., Lateef A; Department of Rheumatology, Division of Medicine, Woodlands Health, Singapore, Singapore., Luo SF; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China., Wu YJ; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China., Navarra S; Section of Rheumatology, University of Santo Tomas Hospital, Manila, Philippines., Zamora L; Section of Rheumatology, University of Santo Tomas Hospital, Manila, Philippines., Li Z; Department of Rheumatology and Immunology, People's Hospital, Peking University Health Science Center, Beijing, China., Chen YH; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China., Oon S; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia., Chan M; Department of Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, Tan Tock Seng, Singapore., Sockalingam S; Department of Medicine, Universiti Malaya Medical Centre, Kuala Lumpur, Malaysia., Hao Y; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.; Rheumatology and Immunology department, Peking University First Hospital, Beijing, China., Zhang Z; Rheumatology and Immunology department, Peking University First Hospital, Beijing, China., Bae SC; Hanyang University Hospital for Rheumatic Diseases, Hanyang University Institute for Rheumatology Research and Hanyang Institute of Bioscience and Biotechnology, Seoul, South Korea., Kikuchi J; Department of Internal Medicine, Keio University, Tokyo, Japan., Takeuchi T; Department of Internal Medicine, Keio University, Tokyo, Japan.; Department of Rheumatology and Applied/Clinical Immunology, Saitama Medical University, Saitama, Japan., Katsumata Y; Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan., Basnayake B; Department of Nephrology, Teaching Hospital Kandy, Kandy, Sri Lanka., Goldblatt F; Department of Rheumatology, Flinders Medical Centre, Bedford Park, SA, Australia., O'Neill S; Rheumatology Department, Liverpool Hospital, Liverpool, NSW, Australia.; University of Sydney, Sydney, NSW, Australia., Pek Ling Ng K; Department of Rheumatology, North Shore Hospital, Health New Zealand Waitemata, Auckland, New Zealand., Tugnet N; Department of Rheumatology, Greenlane Clinical Centre, Health New Zealand Auckland, Te Whatu Ora, Auckland, New Zealand., Sapsford M; Department of Rheumatology, Middlemore Hospital, Health New Zealand Counties Manukau, Te Whatu Ora, Auckland, New Zealand., Poh YJ; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore., Tee C; College of Medicine, University of the Philippines, Manila, Philippines., Tee M; College of Medicine, University of the Philippines, Manila, Philippines., Ohkubo N; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Lefeber AO; Novartis Pharma, Basel, Switzerland., Shisha T; Novartis Pharma, Basel, Switzerland., Tanaka Y; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Golder V; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia., Nikpour M; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.; The University of Sydney School of Public Health, Sydney, NSW, Australia., Hoi A; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia., Gergely P; Novartis Pharma, Basel, Switzerland., Morand E; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia.
Source: Arthritis research & therapy [Arthritis Res Ther] 2025 Jul 23; Vol. 27 (1), pp. 155. Date of Electronic Publication: 2025 Jul 23.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prevalence and outcomes of a pilot definition of severe refractory systemic lupus erythematosus: observations from a multinational Asia-Pacific cohort.
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  Data: <searchLink fieldCode="AU" term="%22Kandane-Rathnayake+R%22">Kandane-Rathnayake R</searchLink>; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia. rangi.kandane-rathnayake@monash.edu.<br /><searchLink fieldCode="AU" term="%22Louthrenoo+W%22">Louthrenoo W</searchLink>; Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.<br /><searchLink fieldCode="AU" term="%22Lau+CS%22">Lau CS</searchLink>; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Hamijoyo+L%22">Hamijoyo L</searchLink>; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.<br /><searchLink fieldCode="AU" term="%22Cho+J%22">Cho J</searchLink>; Rheumatology Division, Department of Medicine, National University Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lateef+A%22">Lateef A</searchLink>; Department of Rheumatology, Division of Medicine, Woodlands Health, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Luo+SF%22">Luo SF</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+YJ%22">Wu YJ</searchLink>; Department of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Navarra+S%22">Navarra S</searchLink>; Section of Rheumatology, University of Santo Tomas Hospital, Manila, Philippines.<br /><searchLink fieldCode="AU" term="%22Zamora+L%22">Zamora L</searchLink>; Section of Rheumatology, University of Santo Tomas Hospital, Manila, Philippines.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Rheumatology and Immunology, People's Hospital, Peking University Health Science Center, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China.<br /><searchLink fieldCode="AU" term="%22Oon+S%22">Oon S</searchLink>; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+M%22">Chan M</searchLink>; Department of Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, Tan Tock Seng, Singapore.<br /><searchLink fieldCode="AU" term="%22Sockalingam+S%22">Sockalingam S</searchLink>; Department of Medicine, Universiti Malaya Medical Centre, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Hao+Y%22">Hao Y</searchLink>; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.; Rheumatology and Immunology department, Peking University First Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Rheumatology and Immunology department, Peking University First Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Bae+SC%22">Bae SC</searchLink>; Hanyang University Hospital for Rheumatic Diseases, Hanyang University Institute for Rheumatology Research and Hanyang Institute of Bioscience and Biotechnology, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kikuchi+J%22">Kikuchi J</searchLink>; Department of Internal Medicine, Keio University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+T%22">Takeuchi T</searchLink>; Department of Internal Medicine, Keio University, Tokyo, Japan.; Department of Rheumatology and Applied/Clinical Immunology, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Katsumata+Y%22">Katsumata Y</searchLink>; Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Basnayake+B%22">Basnayake B</searchLink>; Department of Nephrology, Teaching Hospital Kandy, Kandy, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Goldblatt+F%22">Goldblatt F</searchLink>; Department of Rheumatology, Flinders Medical Centre, Bedford Park, SA, Australia.<br /><searchLink fieldCode="AU" term="%22O'Neill+S%22">O'Neill S</searchLink>; Rheumatology Department, Liverpool Hospital, Liverpool, NSW, Australia.; University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Pek+Ling+Ng+K%22">Pek Ling Ng K</searchLink>; Department of Rheumatology, North Shore Hospital, Health New Zealand Waitemata, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Tugnet+N%22">Tugnet N</searchLink>; Department of Rheumatology, Greenlane Clinical Centre, Health New Zealand Auckland, Te Whatu Ora, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Sapsford+M%22">Sapsford M</searchLink>; Department of Rheumatology, Middlemore Hospital, Health New Zealand Counties Manukau, Te Whatu Ora, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Poh+YJ%22">Poh YJ</searchLink>; Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tee+C%22">Tee C</searchLink>; College of Medicine, University of the Philippines, Manila, Philippines.<br /><searchLink fieldCode="AU" term="%22Tee+M%22">Tee M</searchLink>; College of Medicine, University of the Philippines, Manila, Philippines.<br /><searchLink fieldCode="AU" term="%22Ohkubo+N%22">Ohkubo N</searchLink>; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Lefeber+AO%22">Lefeber AO</searchLink>; Novartis Pharma, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Shisha+T%22">Shisha T</searchLink>; Novartis Pharma, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tanaka+Y%22">Tanaka Y</searchLink>; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.<br /><searchLink fieldCode="AU" term="%22Golder+V%22">Golder V</searchLink>; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Nikpour+M%22">Nikpour M</searchLink>; Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.; The University of Sydney School of Public Health, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Hoi+A%22">Hoi A</searchLink>; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Gergely+P%22">Gergely P</searchLink>; Novartis Pharma, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Morand+E%22">Morand E</searchLink>; Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, VIC, Clayton, Australia.; Rheumatology Department, Monash Health, Clayton, VIC, Australia.
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