Coagulopathy, injury severity and bleeding progression but not prior antiplatelet and anticoagulation therapies drive prognosis in patients with moderate to severe traumatic brain injury.

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Title: Coagulopathy, injury severity and bleeding progression but not prior antiplatelet and anticoagulation therapies drive prognosis in patients with moderate to severe traumatic brain injury.
Authors: Lieschke F; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Marggrander DT; Department of Anaesthesiology, Intensive Care and Pain Therapy, Sana Hospital Offenbach, Offenbach, Germany.; Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum der Charité, Berlin, Germany., Kohlhase KD; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Touma D; Faculty of Medicine, Goethe University Frankfurt, Frankfurt, Germany., Schaefer JH; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Reitz SC; Department of Neurosurgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Konczalla J; Department of Neurosurgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Schindler CR; Department of Traumatology, Hand and Reconstructive Surgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Grefkes C; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany., Bohmann FO; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Source: Frontiers in neurology [Front Neurol] 2025 Jul 09; Vol. 16, pp. 1592583. Date of Electronic Publication: 2025 Jul 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101546899 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2295 (Print) Linking ISSN: 16642295 NLM ISO Abbreviation: Front Neurol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Coagulopathy, injury severity and bleeding progression but not prior antiplatelet and anticoagulation therapies drive prognosis in patients with moderate to severe traumatic brain injury.
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  Data: <searchLink fieldCode="AU" term="%22Lieschke+F%22">Lieschke F</searchLink>; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Marggrander+DT%22">Marggrander DT</searchLink>; Department of Anaesthesiology, Intensive Care and Pain Therapy, Sana Hospital Offenbach, Offenbach, Germany.; Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum der Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kohlhase+KD%22">Kohlhase KD</searchLink>; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Touma+D%22">Touma D</searchLink>; Faculty of Medicine, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Schaefer+JH%22">Schaefer JH</searchLink>; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Reitz+SC%22">Reitz SC</searchLink>; Department of Neurosurgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Konczalla+J%22">Konczalla J</searchLink>; Department of Neurosurgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Schindler+CR%22">Schindler CR</searchLink>; Department of Traumatology, Hand and Reconstructive Surgery, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Grefkes+C%22">Grefkes C</searchLink>; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Bohmann+FO%22">Bohmann FO</searchLink>; Department of Neurology, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101546899%22">Frontiers in neurology</searchLink> [Front Neurol] 2025 Jul 09; Vol. 16, pp. 1592583. <i>Date of Electronic Publication: </i>2025 Jul 09 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101546899 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-2295 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216642295%22">16642295 </searchLink><i>NLM ISO Abbreviation: </i>Front Neurol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fneur.2025.1592583
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              Text: 2025 Jul 09
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