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Harnessing Nanobodies for Precision Targeting of Proteoforms: Opportunities and Challenges in Therapeutics and Diagnostics.

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Title: Harnessing Nanobodies for Precision Targeting of Proteoforms: Opportunities and Challenges in Therapeutics and Diagnostics.
Authors: Van Fossen EM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Rodriguez O; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Berger M; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Wooldridge R; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Gorham L; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Shouaib A; National Security Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Sims AC; National Security Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States., Melchior JT; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States.; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, Ohio 45221, United States.; Department of Neurology, Oregon Heath and Science University, Portland, Oregon 97239, United States., Powell SM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States.
Source: ACS chemical biology [ACS Chem Biol] 2025 Aug 15; Vol. 20 (8), pp. 1817-1827. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article; Review; Research Support, N.I.H., Intramural
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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        Value: 10.1021/acschembio.5c00329
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              Text: 2025 Aug 15
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