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Repositioning of a nutraceutical, scoparone, in the management of MK-801-induced schizophrenia-like behavior in Mice: An insight into SIRT1/PGC-1α/TFAM pathway.

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Title: Repositioning of a nutraceutical, scoparone, in the management of MK-801-induced schizophrenia-like behavior in Mice: An insight into SIRT1/PGC-1α/TFAM pathway.
Authors: Rabie MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt., Marcus WH; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt., Sadek MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt., Ruby HA; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt., Emam KAF; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt., Budzynska B; Independent Laboratory of Behavioral Studies, Medical University of Lublin, 20-093 Lublin, Poland., Skalicka-Wożniak K; Department of Chemistry of Natural Products, Medical University of Lublin, 20-093 Lublin, Poland., Sayed RH; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt., Ahmed LA; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt. Electronic address: lamiaa.ahmed@pharma.cu.edu.eg., El Sayed NS; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.
Source: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 05; Vol. 1004, pp. 177981. Date of Electronic Publication: 2025 Jul 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Repositioning of a nutraceutical, scoparone, in the management of MK-801-induced schizophrenia-like behavior in Mice: An insight into SIRT1/PGC-1α/TFAM pathway.
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  Data: <searchLink fieldCode="AU" term="%22Rabie+MA%22">Rabie MA</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Marcus+WH%22">Marcus WH</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Sadek+MA%22">Sadek MA</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Ruby+HA%22">Ruby HA</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Emam+KAF%22">Emam KAF</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Budzynska+B%22">Budzynska B</searchLink>; Independent Laboratory of Behavioral Studies, Medical University of Lublin, 20-093 Lublin, Poland.<br /><searchLink fieldCode="AU" term="%22Skalicka-Wożniak+K%22">Skalicka-Wożniak K</searchLink>; Department of Chemistry of Natural Products, Medical University of Lublin, 20-093 Lublin, Poland.<br /><searchLink fieldCode="AU" term="%22Sayed+RH%22">Sayed RH</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt; Clinical Pharmacy Department, School of Pharmacy, Newgiza University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+LA%22">Ahmed LA</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt. Electronic address: lamiaa.ahmed@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22El+Sayed+NS%22">El Sayed NS</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy Cairo University, Cairo, 11562, Egypt.
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  Data: <searchLink fieldCode="JN" term="%221254354%22">European journal of pharmacology</searchLink> [Eur J Pharmacol] 2025 Oct 05; Vol. 1004, pp. 177981. <i>Date of Electronic Publication: </i>2025 Jul 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1254354 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0712 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200142999%22">00142999 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2025 Oct 05
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