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Inter- and intra-bacterial strain diversity remains the "elephant in the (living) room".

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Title: Inter- and intra-bacterial strain diversity remains the "elephant in the (living) room".
Authors: Valcek A; Microbial Resistance and Drug Discovery, VIB-VUB Center for Structural Biology, VIB, Flanders Institute for Biotechnology, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium., Kröger C; Department of Microbiology, School of Genetics and Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Dublin 2, Ireland., de Dios R; Centre for Antimicrobial Innovations, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UB8 3PH, UK., McCarthy RR; Centre for Antimicrobial Innovations, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UB8 3PH, UK., Coenye T; Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium., Trent MS; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.; Department of Microbiology, College of Art and Sciences; University of Georgia, Athens, Georgia, USA., Karah N; Department of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University, SE-901 87, Umeå, Sweden., Uhlin BE; Department of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University, SE-901 87, Umeå, Sweden., Classen AY; Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935, Cologne, Germany.; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany., Higgins PG; Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935, Cologne, Germany.; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Ebersberger I; Faculty of Biological Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Frankfurt am Main, Germany.; LOEWE Centre for Translational Biodiversity Genomics (LOEWE-TBG), Frankfurt am Main, Germany., Laaberki MH; Université de Lyon, VetAgro Sup, Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ, Lyon, France., Charpentier X; CIRI, Centre International de Recherche en Infectiologie, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ, Lyon, France., Visca P; Department of Science, Roma Tre University, Rome, Italy., Rather PN; Department of Microbiology and Immunology, Emory University School of Medicine and Research Service, Atlanta VA Medical Center, 30033, Atlanta, GA, USA., Van der Henst C; Microbial Resistance and Drug Discovery, VIB-VUB Center for Structural Biology, VIB, Flanders Institute for Biotechnology, Brussels, Belgium. charles.vanderhenst@vub.vib.be.; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium. charles.vanderhenst@vub.vib.be.
Source: Npj antimicrobials and resistance [NPJ Antimicrob Resist] 2025 Jul 25; Vol. 3 (1), pp. 67. Date of Electronic Publication: 2025 Jul 25.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918804282606676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-8745 (Electronic) Linking ISSN: 27318745 NLM ISO Abbreviation: NPJ Antimicrob Resist Subsets: PubMed not MEDLINE
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  Data: Inter- and intra-bacterial strain diversity remains the "elephant in the (living) room".
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  Data: <searchLink fieldCode="AU" term="%22Valcek+A%22">Valcek A</searchLink>; Microbial Resistance and Drug Discovery, VIB-VUB Center for Structural Biology, VIB, Flanders Institute for Biotechnology, Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Kröger+C%22">Kröger C</searchLink>; Department of Microbiology, School of Genetics and Microbiology, Moyne Institute of Preventive Medicine, Trinity College Dublin, Dublin 2, Ireland.<br /><searchLink fieldCode="AU" term="%22de+Dios+R%22">de Dios R</searchLink>; Centre for Antimicrobial Innovations, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UB8 3PH, UK.<br /><searchLink fieldCode="AU" term="%22McCarthy+RR%22">McCarthy RR</searchLink>; Centre for Antimicrobial Innovations, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UB8 3PH, UK.<br /><searchLink fieldCode="AU" term="%22Coenye+T%22">Coenye T</searchLink>; Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Trent+MS%22">Trent MS</searchLink>; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.; Department of Microbiology, College of Art and Sciences; University of Georgia, Athens, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Karah+N%22">Karah N</searchLink>; Department of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University, SE-901 87, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Uhlin+BE%22">Uhlin BE</searchLink>; Department of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University, SE-901 87, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Classen+AY%22">Classen AY</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935, Cologne, Germany.; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Higgins+PG%22">Higgins PG</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935, Cologne, Germany.; German Centre for Infection Research, partner site Bonn-Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ebersberger+I%22">Ebersberger I</searchLink>; Faculty of Biological Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.; Senckenberg Biodiversity and Climate Research Centre (SBiK-F), Frankfurt am Main, Germany.; LOEWE Centre for Translational Biodiversity Genomics (LOEWE-TBG), Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Laaberki+MH%22">Laaberki MH</searchLink>; Université de Lyon, VetAgro Sup, Lyon, France.; CIRI, Centre International de Recherche en Infectiologie, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Charpentier+X%22">Charpentier X</searchLink>; CIRI, Centre International de Recherche en Infectiologie, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Visca+P%22">Visca P</searchLink>; Department of Science, Roma Tre University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rather+PN%22">Rather PN</searchLink>; Department of Microbiology and Immunology, Emory University School of Medicine and Research Service, Atlanta VA Medical Center, 30033, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Van+der+Henst+C%22">Van der Henst C</searchLink>; Microbial Resistance and Drug Discovery, VIB-VUB Center for Structural Biology, VIB, Flanders Institute for Biotechnology, Brussels, Belgium. charles.vanderhenst@vub.vib.be.; Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium. charles.vanderhenst@vub.vib.be.
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