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A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function.

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Title: A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function.
Authors: Sasse A; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.; Vector Institute, Toronto, Ontario, Canada., Ray D; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Laverty KU; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada.; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tam CL; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Graduate Program in Computational Biology and Medicine, Weill-Cornell Graduate School, New York, NY, USA., Albu M; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Zheng H; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Levdansky Y; National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Lyudovyk O; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Graduate Program in Computational Biology and Medicine, Weill-Cornell Graduate School, New York, NY, USA., Dalal T; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Graduate Program in Computational Biology and Medicine, Weill-Cornell Graduate School, New York, NY, USA., Nie K; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Vector Institute, Toronto, Ontario, Canada., Magis C; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Notredame C; Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Valkov E; National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Weirauch MT; Center for Autoimmune Genomics and Etiology, Divisions of Allergy and Immunology, Human Genetics, Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital, Cincinnati, OH, USA. matthew.weirauch@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. matthew.weirauch@cchmc.org., Hughes TR; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. t.hughes@utoronto.ca.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. t.hughes@utoronto.ca., Morris Q; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. morrisq@mskcc.org.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. morrisq@mskcc.org.; Vector Institute, Toronto, Ontario, Canada. morrisq@mskcc.org.; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. morrisq@mskcc.org.; Graduate Program in Computational Biology and Medicine, Weill-Cornell Graduate School, New York, NY, USA. morrisq@mskcc.org.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada. morrisq@mskcc.org.
Source: Nature biotechnology [Nat Biotechnol] 2026 Jul; Vol. 44 (7), pp. 1226-1236. Date of Electronic Publication: 2025 Jul 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
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