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Single-atom Pt-doped ceria nanozymes mitigate myocardial ischemia reperfusion injury via cardiomyocyte-targeted uptake and suppression of reactive oxygen species.

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Title: Single-atom Pt-doped ceria nanozymes mitigate myocardial ischemia reperfusion injury via cardiomyocyte-targeted uptake and suppression of reactive oxygen species.
Authors: Pu A; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China., Sim WS; Department of Biomedicine & Health Sciences, The Catholic University of Korea, Seoul, Republic of Korea.; Division of Cardiology, Department of Internal Medicine, Uijeongbu St. Mary's Hospial, Uijeongbu, Republic of Korea., Ji Y; Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea.; Department of Nanobiomedical Science & BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea., Kurian AG; Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea.; Department of Nanobiomedical Science & BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea., Lee JH; Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea.; Department of Nanobiomedical Science & BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea.; Department of Biomaterials Science, School of Dentistry, Dankook University, Cheonan, 31116, Republic of Korea.; Cell & Matter Institute, Dankook University, Cheonan, 31116, Republic of Korea.; Mechanobiology Dental Medicine Research Center, Dankook University, Cheonan, 31116, Republic of Korea., Van Anh Bui T; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China., Lai Y; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China., Hwangbo H; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China., Sun H; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China., Kim HW; Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea.; Department of Nanobiomedical Science & BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea.; Department of Biomaterials Science, School of Dentistry, Dankook University, Cheonan, 31116, Republic of Korea.; Cell & Matter Institute, Dankook University, Cheonan, 31116, Republic of Korea.; Mechanobiology Dental Medicine Research Center, Dankook University, Cheonan, 31116, Republic of Korea., Park HJ; Department of Biomedicine & Health Sciences, The Catholic University of Korea, Seoul, Republic of Korea.; Division of Cardiology, Department of Internal Medicine, Uijeongbu St. Mary's Hospial, Uijeongbu, Republic of Korea.; Cell Death Disease Research Center, The Catholic University of Korea, Seoul, Republic of Korea., Ban K; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong, China.; Tung Biomedical Sciences Centre, City University of Hong Kong, Kowloon, Hong Kong, China.
Source: Bioactive materials [Bioact Mater] 2025 Jul 20; Vol. 53, pp. 366-385. Date of Electronic Publication: 2025 Jul 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ke Ai Publishing Country of Publication: China NLM ID: 101685294 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-199X (Electronic) Linking ISSN: 2452199X NLM ISO Abbreviation: Bioact Mater Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2452-199X
DOI:10.1016/j.bioactmat.2025.07.019