Reductive stress induces unresolved ER stress and proteotoxic cardiomyopathy.

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Title: Reductive stress induces unresolved ER stress and proteotoxic cardiomyopathy.
Authors: Sunny S; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Radhakrishnan RK; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Devarajan A; Department of Medicine, University of California Los Angeles, Los Angeles, USA., Masjoan Juncos JX; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bansal M; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Ouyang X; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Zhang J; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Xie M; Comprehensive Cardiovascular Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Litovsky SH; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Trinity JD; Geriatric Research, Education, and Clinical Center (GRECC), Salt Lake City Veteran Affairs Medical Center, Salt Lake, UT, USA., Might M; Precision Medicine Institute, University of Alabama at Birmingham, Birmingham, AL, USA., Pogwizd SM; Comprehensive Cardiovascular Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Kontaridis MI; Department of Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, NY, 13501, USA; Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA., Rajasekaran NS; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA; Geriatric Research, Education, and Clinical Center (GRECC), Salt Lake City Veteran Affairs Medical Center, Salt Lake, UT, USA; Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah 84112, USA. Electronic address: rajnsr@uabmc.edu.
Source: Redox biology [Redox Biol] 2025 Oct; Vol. 86, pp. 103713. Date of Electronic Publication: 2025 Jun 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Reductive stress induces unresolved ER stress and proteotoxic cardiomyopathy.
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  Data: <searchLink fieldCode="AU" term="%22Sunny+S%22">Sunny S</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Radhakrishnan+RK%22">Radhakrishnan RK</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Devarajan+A%22">Devarajan A</searchLink>; Department of Medicine, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Masjoan+Juncos+JX%22">Masjoan Juncos JX</searchLink>; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Bansal+M%22">Bansal M</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Ouyang+X%22">Ouyang X</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Xie+M%22">Xie M</searchLink>; Comprehensive Cardiovascular Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Litovsky+SH%22">Litovsky SH</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Trinity+JD%22">Trinity JD</searchLink>; Geriatric Research, Education, and Clinical Center (GRECC), Salt Lake City Veteran Affairs Medical Center, Salt Lake, UT, USA.<br /><searchLink fieldCode="AU" term="%22Might+M%22">Might M</searchLink>; Precision Medicine Institute, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Pogwizd+SM%22">Pogwizd SM</searchLink>; Comprehensive Cardiovascular Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Kontaridis+MI%22">Kontaridis MI</searchLink>; Department of Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, NY, 13501, USA; Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Rajasekaran+NS%22">Rajasekaran NS</searchLink>; Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology/Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA; Geriatric Research, Education, and Clinical Center (GRECC), Salt Lake City Veteran Affairs Medical Center, Salt Lake, UT, USA; Division of Cardiovascular Medicine, Department of Medicine, University of Utah, Salt Lake City, Utah 84112, USA. Electronic address: rajnsr@uabmc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101605639%22">Redox biology</searchLink> [Redox Biol] 2025 Oct; Vol. 86, pp. 103713. <i>Date of Electronic Publication: </i>2025 Jun 09.
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  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+B%2EV%22">Elsevier, B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101605639 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-2317 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222132317%22">22132317 </searchLink><i>NLM ISO Abbreviation: </i>Redox Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.redox.2025.103713
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        Text: English
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