Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1.
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| Title: | Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1. |
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| Authors: | Choi R; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., Hulverson MA; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., Schaefer DA; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America., Betzer DP; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America., Riggs MW; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America., Huang W; Department of Biochemistry, University of Washington, Seattle, Washington United States of America., Sun V; Department of Pharmaceutics, University of Washington, Seattle, Washington United States of America., Whitman GR; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., McCloskey MC; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., Marsh K; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Buck WR; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Wagner DS; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Yang J; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Bowman AP; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Ciurlionis R; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America., Ajiboye J; Cellular, Molecular and Biomedical Sciences Graduate Program, University of Vermont, Burlington, Vermont United States of America.; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Hemphill A; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Sigalapalli DK; Department of Biochemistry, University of Washington, Seattle, Washington United States of America., Arnold SLM; Department of Pharmaceutics, University of Washington, Seattle, Washington United States of America., Barrett LK; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., Ojo KK; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America., Fan E; Department of Biochemistry, University of Washington, Seattle, Washington United States of America., Van Voorhis WC; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America. |
| Source: | PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Jul 30; Vol. 19 (7), pp. e0013263. Date of Electronic Publication: 2025 Jul 30 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40737275 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Choi+R%22">Choi R</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Hulverson+MA%22">Hulverson MA</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Schaefer+DA%22">Schaefer DA</searchLink>; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Betzer+DP%22">Betzer DP</searchLink>; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Riggs+MW%22">Riggs MW</searchLink>; School of Animal and Comparative Biomedical Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Department of Biochemistry, University of Washington, Seattle, Washington United States of America.<br /><searchLink fieldCode="AU" term="%22Sun+V%22">Sun V</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington United States of America.<br /><searchLink fieldCode="AU" term="%22Whitman+GR%22">Whitman GR</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22McCloskey+MC%22">McCloskey MC</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Marsh+K%22">Marsh K</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Buck+WR%22">Buck WR</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Wagner+DS%22">Wagner DS</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Bowman+AP%22">Bowman AP</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Ciurlionis+R%22">Ciurlionis R</searchLink>; Research and Development, AbbVie Inc, North Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Ajiboye+J%22">Ajiboye J</searchLink>; Cellular, Molecular and Biomedical Sciences Graduate Program, University of Vermont, Burlington, Vermont United States of America.; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hemphill+A%22">Hemphill A</searchLink>; Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sigalapalli+DK%22">Sigalapalli DK</searchLink>; Department of Biochemistry, University of Washington, Seattle, Washington United States of America.<br /><searchLink fieldCode="AU" term="%22Arnold+SLM%22">Arnold SLM</searchLink>; Department of Pharmaceutics, University of Washington, Seattle, Washington United States of America.<br /><searchLink fieldCode="AU" term="%22Barrett+LK%22">Barrett LK</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Ojo+KK%22">Ojo KK</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Fan+E%22">Fan E</searchLink>; Department of Biochemistry, University of Washington, Seattle, Washington United States of America.<br /><searchLink fieldCode="AU" term="%22Van+Voorhis+WC%22">Van Voorhis WC</searchLink>; Department of Medicine, Division of Allergy and Infectious Diseases, Center for Emerging and Re-emerging Infectious Disease (CERID), University of Washington, Seattle, Washington, United States of America. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101291488%22">PLoS neglected tropical diseases</searchLink> [PLoS Negl Trop Dis] 2025 Jul 30; Vol. 19 (7), pp. e0013263. <i>Date of Electronic Publication: </i>2025 Jul 30 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101291488 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1935-2735 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219352727%22">19352727 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Negl Trop Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40737275 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pntd.0013263 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0013263 Titles: – TitleFull: Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Choi R – PersonEntity: Name: NameFull: Hulverson MA – PersonEntity: Name: NameFull: Schaefer DA – PersonEntity: Name: NameFull: Betzer DP – PersonEntity: Name: NameFull: Riggs MW – PersonEntity: Name: NameFull: Huang W – PersonEntity: Name: NameFull: Sun V – PersonEntity: Name: NameFull: Whitman GR – PersonEntity: Name: NameFull: McCloskey MC – PersonEntity: Name: NameFull: Marsh K – PersonEntity: Name: NameFull: Buck WR – PersonEntity: Name: NameFull: Wagner DS – PersonEntity: Name: NameFull: Yang J – PersonEntity: Name: NameFull: Bowman AP – PersonEntity: Name: NameFull: Ciurlionis R – PersonEntity: Name: NameFull: Ajiboye J – PersonEntity: Name: NameFull: Hemphill A – PersonEntity: Name: NameFull: Sigalapalli DK – PersonEntity: Name: NameFull: Arnold SLM – PersonEntity: Name: NameFull: Barrett LK – PersonEntity: Name: NameFull: Ojo KK – PersonEntity: Name: NameFull: Fan E – PersonEntity: Name: NameFull: Van Voorhis WC IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 07 Text: 2025 Jul 30 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1935-2735 Numbering: – Type: volume Value: 19 – Type: issue Value: 7 Titles: – TitleFull: PLoS neglected tropical diseases Type: main |
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