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Characterisation of a clinical trial-like population of high cardiovascular risk patients prior to myocardial infarction or stroke in the real world: design and protocol for a multidatabase retrospective cohort study.

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Title: Characterisation of a clinical trial-like population of high cardiovascular risk patients prior to myocardial infarction or stroke in the real world: design and protocol for a multidatabase retrospective cohort study.
Authors: Ochs A; Center for Observational Research, Amgen Ltd, Uxbridge, UK aochs@amgen.com., Chan Q; Center for Observational Research, Amgen Ltd, Uxbridge, UK., Dhalwani NN; Center for Observational Research, Amgen Inc, Thousand Oaks, California, USA., Duxbury M; Center for Observational Research, Amgen Ltd, Uxbridge, UK., Shannon E; Center for Observational Research, Amgen Inc, Thousand Oaks, California, USA., O'Kelly J; Center for Observational Research, Amgen Ltd, Uxbridge, UK., Paiva da Silva Lima G; Global Development, Amgen Inc, Thousand Oaks, California, USA., Avcil S; Global Development, Amgen Inc, Thousand Oaks, California, USA., Chan AY; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Chui CS; Laboratory of Data Discovery for Health (D24H), Hong Kong Science and Technology Park, Sha Tin, Hong Kong SAR, China.; School of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.; Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR, China., Lai EC; Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Taiwan, Taiwan.; Population Health Data Center, National Cheng Kung University, Tainan, Taiwan., Cars T; Sence Research, Uppsala, Sweden., Shin JJ; School of Pharmacy, Sungkyunkwan University-Suwon Campus, Suwon, Gyeonggi-do, Republic of Korea., Heintjes EM; PHARMO Institute, Utrecht, The Netherlands., Wong IC; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.; Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR, China.; Aston Pharmacy School, Aston University, Birmingham, UK.
Source: BMJ open [BMJ Open] 2025 Jul 30; Vol. 15 (7), pp. e092702. Date of Electronic Publication: 2025 Jul 30.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Characterisation of a clinical trial-like population of high cardiovascular risk patients prior to myocardial infarction or stroke in the real world: design and protocol for a multidatabase retrospective cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Ochs+A%22">Ochs A</searchLink>; Center for Observational Research, Amgen Ltd, Uxbridge, UK aochs@amgen.com.<br /><searchLink fieldCode="AU" term="%22Chan+Q%22">Chan Q</searchLink>; Center for Observational Research, Amgen Ltd, Uxbridge, UK.<br /><searchLink fieldCode="AU" term="%22Dhalwani+NN%22">Dhalwani NN</searchLink>; Center for Observational Research, Amgen Inc, Thousand Oaks, California, USA.<br /><searchLink fieldCode="AU" term="%22Duxbury+M%22">Duxbury M</searchLink>; Center for Observational Research, Amgen Ltd, Uxbridge, UK.<br /><searchLink fieldCode="AU" term="%22Shannon+E%22">Shannon E</searchLink>; Center for Observational Research, Amgen Inc, Thousand Oaks, California, USA.<br /><searchLink fieldCode="AU" term="%22O'Kelly+J%22">O'Kelly J</searchLink>; Center for Observational Research, Amgen Ltd, Uxbridge, UK.<br /><searchLink fieldCode="AU" term="%22Paiva+da+Silva+Lima+G%22">Paiva da Silva Lima G</searchLink>; Global Development, Amgen Inc, Thousand Oaks, California, USA.<br /><searchLink fieldCode="AU" term="%22Avcil+S%22">Avcil S</searchLink>; Global Development, Amgen Inc, Thousand Oaks, California, USA.<br /><searchLink fieldCode="AU" term="%22Chan+AY%22">Chan AY</searchLink>; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chui+CS%22">Chui CS</searchLink>; Laboratory of Data Discovery for Health (D24H), Hong Kong Science and Technology Park, Sha Tin, Hong Kong SAR, China.; School of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.; Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lai+EC%22">Lai EC</searchLink>; Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Taiwan, Taiwan.; Population Health Data Center, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cars+T%22">Cars T</searchLink>; Sence Research, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Shin+JJ%22">Shin JJ</searchLink>; School of Pharmacy, Sungkyunkwan University-Suwon Campus, Suwon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heintjes+EM%22">Heintjes EM</searchLink>; PHARMO Institute, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wong+IC%22">Wong IC</searchLink>; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.; Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR, China.; Aston Pharmacy School, Aston University, Birmingham, UK.
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              Text: 2025 Jul 30
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