Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial.
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| Title: | Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial. |
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| Authors: | Abdel Jawad M; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA., Furtado RHM; Brazilian Clinical Research Institute, Sao Paulo, Brazil., Esterline R; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gaithersburg, MD, USA., Oscarsson J; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden., Gasparyan SB; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Boston, MA, USA., Koch GG; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Martinez F; National University of Cordoba, Avenida Colon 2057, Córdoba, Argentina., Mukhtar O; Experimental Medicine & Immunotherapeutics Division, Department of Medicine, University of Cambridge, Cambridge, UK., Verma S; Division of Cardiac Surgery, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada.; Department of Surgery, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Langkilde AM; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden., Ambery P; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden., Patel S; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA., Gosch K; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA., Windsor SL; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA., Soares RVP; Academic Research Organization- Einstein Hospital Israelita, Av. Albert Einstein 627, Sao Paulo-SP, Brazil., Moia DDF; Academic Research Organization- Einstein Hospital Israelita, Av. Albert Einstein 627, Sao Paulo-SP, Brazil., Aboudara M; Division of Pulmonary and Critical Care, Saint Luke's Health System, Kansas City, MO, USA., Javaheri A; Washington University School of Medicine and John Cochran VA Hospital, St. Louis, MO, USA., Saraiva JFK; Instituto de Pesquisa Clinica de Campinas, Campinas, Brazil., Maia LN; Centro Integrado de Pesquisas (CIP), Hospital de Base, Sao Jose Do Rio Preto, Brazil., Berwanger O; Imperial College London, London, UK.; George Institute for Global Health UK, London, UK., Sauer AJ; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA. asauer@saint-lukes.org.; University of Missouri-Kansas City, Kansas City, MO, USA. asauer@saint-lukes.org., Kosiborod MN; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA.; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Boston, MA, USA. |
| Source: | Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Jul 30; Vol. 24 (1), pp. 307. Date of Electronic Publication: 2025 Jul 30. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40739638 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Abdel+Jawad+M%22">Abdel Jawad M</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Furtado+RHM%22">Furtado RHM</searchLink>; Brazilian Clinical Research Institute, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Esterline+R%22">Esterline R</searchLink>; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Oscarsson+J%22">Oscarsson J</searchLink>; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Gasparyan+SB%22">Gasparyan SB</searchLink>; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Koch+GG%22">Koch GG</searchLink>; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+F%22">Martinez F</searchLink>; National University of Cordoba, Avenida Colon 2057, Córdoba, Argentina.<br /><searchLink fieldCode="AU" term="%22Mukhtar+O%22">Mukhtar O</searchLink>; Experimental Medicine & Immunotherapeutics Division, Department of Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Verma+S%22">Verma S</searchLink>; Division of Cardiac Surgery, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada.; Department of Surgery, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Langkilde+AM%22">Langkilde AM</searchLink>; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ambery+P%22">Ambery P</searchLink>; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gosch+K%22">Gosch K</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Windsor+SL%22">Windsor SL</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Soares+RVP%22">Soares RVP</searchLink>; Academic Research Organization- Einstein Hospital Israelita, Av. Albert Einstein 627, Sao Paulo-SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Moia+DDF%22">Moia DDF</searchLink>; Academic Research Organization- Einstein Hospital Israelita, Av. Albert Einstein 627, Sao Paulo-SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Aboudara+M%22">Aboudara M</searchLink>; Division of Pulmonary and Critical Care, Saint Luke's Health System, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Javaheri+A%22">Javaheri A</searchLink>; Washington University School of Medicine and John Cochran VA Hospital, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Saraiva+JFK%22">Saraiva JFK</searchLink>; Instituto de Pesquisa Clinica de Campinas, Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Maia+LN%22">Maia LN</searchLink>; Centro Integrado de Pesquisas (CIP), Hospital de Base, Sao Jose Do Rio Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Berwanger+O%22">Berwanger O</searchLink>; Imperial College London, London, UK.; George Institute for Global Health UK, London, UK.<br /><searchLink fieldCode="AU" term="%22Sauer+AJ%22">Sauer AJ</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA. asauer@saint-lukes.org.; University of Missouri-Kansas City, Kansas City, MO, USA. asauer@saint-lukes.org.<br /><searchLink fieldCode="AU" term="%22Kosiborod+MN%22">Kosiborod MN</searchLink>; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.; University of Missouri-Kansas City, Kansas City, MO, USA.; Late-Stage Development, CVRM, AstraZeneca, BioPharmaceuticals R&D, Boston, MA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101147637%22">Cardiovascular diabetology</searchLink> [Cardiovasc Diabetol] 2025 Jul 30; Vol. 24 (1), pp. 307. <i>Date of Electronic Publication: </i>2025 Jul 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147637 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1475-2840 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214752840%22">14752840 </searchLink><i>NLM ISO Abbreviation: </i>Cardiovasc Diabetol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40739638 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12933-025-02875-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 307 Titles: – TitleFull: Efficacy and safety of dapagliflozin in patients hospitalized with COVID-19 with and without type 2 diabetes: a prespecified analysis of the DARE-19 randomized trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Abdel Jawad M – PersonEntity: Name: NameFull: Furtado RHM – PersonEntity: Name: NameFull: Esterline R – PersonEntity: Name: NameFull: Oscarsson J – PersonEntity: Name: NameFull: Gasparyan SB – PersonEntity: Name: NameFull: Koch GG – PersonEntity: Name: NameFull: Martinez F – PersonEntity: Name: NameFull: Mukhtar O – PersonEntity: Name: NameFull: Verma S – PersonEntity: Name: NameFull: Langkilde AM – PersonEntity: Name: NameFull: Ambery P – PersonEntity: Name: NameFull: Patel S – PersonEntity: Name: NameFull: Gosch K – PersonEntity: Name: NameFull: Windsor SL – PersonEntity: Name: NameFull: Soares RVP – PersonEntity: Name: NameFull: Moia DDF – PersonEntity: Name: NameFull: Aboudara M – PersonEntity: Name: NameFull: Javaheri A – PersonEntity: Name: NameFull: Saraiva JFK – PersonEntity: Name: NameFull: Maia LN – PersonEntity: Name: NameFull: Berwanger O – PersonEntity: Name: NameFull: Sauer AJ – PersonEntity: Name: NameFull: Kosiborod MN IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 07 Text: 2025 Jul 30 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1475-2840 Numbering: – Type: volume Value: 24 – Type: issue Value: 1 Titles: – TitleFull: Cardiovascular diabetology Type: main |
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