Loss of p21 does not protect against premature ovarian insufficiency caused by alkylating agents.

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Title: Loss of p21 does not protect against premature ovarian insufficiency caused by alkylating agents.
Authors: Lu X; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Han Y; Department of Nursing, Changzhou Hygiene Vocational Technology College, Changzhou, Jiangsu, China., Song J; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Wan Q; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Liu P; The Department of Animal Center, Kebiao Medical Testing Center, Changzhou, Jiangsu, China., Chen L; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Wang Y; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Xue P; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China., Dai X; The Center for Reproductive Medicine, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Jul 16; Vol. 16, pp. 1616965. Date of Electronic Publication: 2025 Jul 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-2392
DOI:10.3389/fendo.2025.1616965