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Ophthalmological Question Answering and Reasoning Using OpenAI o1 vs Other Large Language Models.

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Title: Ophthalmological Question Answering and Reasoning Using OpenAI o1 vs Other Large Language Models.
Authors: Srinivasan S; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Ai X; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Zou M; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Zou K; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Kim H; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Lo TWS; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Pushpanathan K; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Yang GD; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Goh JHL; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Kong Y; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Li A; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Singer MB; Department of Ophthalmology and Visual Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Jin K; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China., Antaki F; Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.; CHUM School of Artificial Intelligence in Healthcare, Montreal, Quebec, Canada., Chen DZ; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Department of Ophthalmology, National University Hospital, Singapore., Liu D; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Adelman RA; Department of Ophthalmology and Visual Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Chen Q; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut., Tham YC; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Eye Academic Clinical Program, Duke NUS Medical School, Singapore.
Source: JAMA ophthalmology [JAMA Ophthalmol] 2025 Sep 01; Vol. 143 (9), pp. 740-748.
Publication Type: Journal Article
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589539 Publication Model: Print Cited Medium: Internet ISSN: 2168-6173 (Electronic) Linking ISSN: 21686165 NLM ISO Abbreviation: JAMA Ophthalmol Subsets: MEDLINE
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  Data: Ophthalmological Question Answering and Reasoning Using OpenAI o1 vs Other Large Language Models.
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  Data: <searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Ai+X%22">Ai X</searchLink>; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Zou+M%22">Zou M</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Zou+K%22">Zou K</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Lo+TWS%22">Lo TWS</searchLink>; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Pushpanathan+K%22">Pushpanathan K</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yang+GD%22">Yang GD</searchLink>; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+JHL%22">Goh JHL</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.<br /><searchLink fieldCode="AU" term="%22Kong+Y%22">Kong Y</searchLink>; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Singer+MB%22">Singer MB</searchLink>; Department of Ophthalmology and Visual Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Jin+K%22">Jin K</searchLink>; Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Antaki+F%22">Antaki F</searchLink>; Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.; CHUM School of Artificial Intelligence in Healthcare, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+DZ%22">Chen DZ</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Department of Ophthalmology, National University Hospital, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Adelman+RA%22">Adelman RA</searchLink>; Department of Ophthalmology and Visual Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Department of Biomedical Informatics and Data Science, Yale School of Medicine, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Tham+YC%22">Tham YC</searchLink>; Centre for Innovation and Precision Eye Health, Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Eye Academic Clinical Program, Duke NUS Medical School, Singapore.
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