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SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands.

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Title: SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands.
Authors: Hardwick JS; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., Dhir S; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Kirchner A; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Simeone A; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Flynn SM; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Edgerton JM; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom., de Cesaris Araujo Tavares R; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Esain-Garcia I; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Tannahill D; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom., Golder P; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom., Monahan JM; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom., Gosal WS; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom., Balasubramanian S; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.; School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, United Kingdom.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Aug 05; Vol. 122 (31), pp. e2512204122. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: SCoTCH-seq reveals that 5-hydroxymethylcytosine encodes regulatory information across DNA strands.
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  Data: <searchLink fieldCode="AU" term="%22Hardwick+JS%22">Hardwick JS</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dhir+S%22">Dhir S</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kirchner+A%22">Kirchner A</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Simeone+A%22">Simeone A</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Flynn+SM%22">Flynn SM</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Edgerton+JM%22">Edgerton JM</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.<br /><searchLink fieldCode="AU" term="%22de+Cesaris+Araujo+Tavares+R%22">de Cesaris Araujo Tavares R</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Esain-Garcia+I%22">Esain-Garcia I</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tannahill+D%22">Tannahill D</searchLink>; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Golder+P%22">Golder P</searchLink>; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Monahan+JM%22">Monahan JM</searchLink>; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gosal+WS%22">Gosal WS</searchLink>; biomodal Ltd., The Trinity Building, Cambridge CB10 1TS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Balasubramanian+S%22">Balasubramanian S</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.; Cancer Research UK Cambridge institute, University of Cambridge, Cambridge CB2 0RE, United Kingdom.; School of Clinical Medicine, University of Cambridge, Cambridge CB2 0SP, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2025 Aug 05; Vol. 122 (31), pp. e2512204122. <i>Date of Electronic Publication: </i>2025 Jul 31.
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