Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival.
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| Title: | Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival. |
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| Authors: | Hissong E; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Bhinder B; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Kim J; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Ohara K; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Ravichandran H; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Assaad MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Elsoukkary S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA., Shusterman M; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA., Khan U; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA., Eng KW; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Bareja R; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Manohar J; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Sigouros M; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA., Rendeiro AF; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, Wien 1090, Austria., Jessurun J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA., Ocean AJ; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA., Sboner A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA., Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA., Mosquera JM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA. Electronic address: jmm9018@med.cornell.edu., Shah MA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA. Electronic address: mas9313@med.cornell.edu. |
| Source: | Pathology, research and practice [Pathol Res Pract] 2025 Sep; Vol. 273, pp. 156150. Date of Electronic Publication: 2025 Jul 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40743578 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hissong+E%22">Hissong E</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Bhinder+B%22">Bhinder B</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Ohara+K%22">Ohara K</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Ravichandran+H%22">Ravichandran H</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Assaad+MA%22">Assaad MA</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Elsoukkary+S%22">Elsoukkary S</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Shusterman+M%22">Shusterman M</searchLink>; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Khan+U%22">Khan U</searchLink>; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Eng+KW%22">Eng KW</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Bareja+R%22">Bareja R</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Manohar+J%22">Manohar J</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Sigouros+M%22">Sigouros M</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA.<br /><searchLink fieldCode="AU" term="%22Rendeiro+AF%22">Rendeiro AF</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, Wien 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Jessurun+J%22">Jessurun J</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Ocean+AJ%22">Ocean AJ</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sboner+A%22">Sboner A</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Elemento+O%22">Elemento O</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, 525 E 68th St., New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mosquera+JM%22">Mosquera JM</searchLink>; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 525 E 68th St, New York, NY 10065, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA. Electronic address: jmm9018@med.cornell.edu.<br /><searchLink fieldCode="AU" term="%22Shah+MA%22">Shah MA</searchLink>; Englander Institute for Precision Medicine, Weill Cornell Medicine and New York Presbyterian, 413 E 69th St, New York, NY 10021, USA; Department of Medicine, Hematology and Medical Oncology, Weill Cornell Medicine, 525 E 68th St, New York, NY, USA. Electronic address: mas9313@med.cornell.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227806109%22">Pathology, research and practice</searchLink> [Pathol Res Pract] 2025 Sep; Vol. 273, pp. 156150. <i>Date of Electronic Publication: </i>2025 Jul 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Gustav+Fischer+Verlag%22">Gustav Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>7806109 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-0631 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203440338%22">03440338 </searchLink><i>NLM ISO Abbreviation: </i>Pathol Res Pract <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.prp.2025.156150 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 156150 Titles: – TitleFull: Integrative transcriptomic and single-cell protein characterization of colorectal carcinoma delineates distinct tumor immune microenvironments associated with overall survival. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hissong E – PersonEntity: Name: NameFull: Bhinder B – PersonEntity: Name: NameFull: Kim J – PersonEntity: Name: NameFull: Ohara K – PersonEntity: Name: NameFull: Ravichandran H – PersonEntity: Name: NameFull: Assaad MA – PersonEntity: Name: NameFull: Elsoukkary S – PersonEntity: Name: NameFull: Shusterman M – PersonEntity: Name: NameFull: Khan U – PersonEntity: Name: NameFull: Eng KW – PersonEntity: Name: NameFull: Bareja R – PersonEntity: Name: NameFull: Manohar J – PersonEntity: Name: NameFull: Sigouros M – PersonEntity: Name: NameFull: Rendeiro AF – PersonEntity: Name: NameFull: Jessurun J – PersonEntity: Name: NameFull: Ocean AJ – PersonEntity: Name: NameFull: Sboner A – PersonEntity: Name: NameFull: Elemento O – PersonEntity: Name: NameFull: Mosquera JM – PersonEntity: Name: NameFull: Shah MA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2025 Sep Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1618-0631 Numbering: – Type: volume Value: 273 Titles: – TitleFull: Pathology, research and practice Type: main |
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