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Triflumizole induces excessive reactive oxygen species, inhibits the GPR30/PI3K/AKT pathway, and triggers apoptosis and autophagy in GC-1 spermatogonia cells.

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Title: Triflumizole induces excessive reactive oxygen species, inhibits the GPR30/PI3K/AKT pathway, and triggers apoptosis and autophagy in GC-1 spermatogonia cells.
Authors: Kim SG; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Yoon DJ; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Varias DC; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Ahn GJ; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Han GU; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Moon SH; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Lee HS; Department of Food Science and Biotechnology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea; Department of Food Safety and Regulatory Science, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Shin SH; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea., Ryu BY; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea. Electronic address: byryu@cau.ac.kr.
Source: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2025 Sep; Vol. 213, pp. 106486. Date of Electronic Publication: 2025 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Triflumizole induces excessive reactive oxygen species, inhibits the GPR30/PI3K/AKT pathway, and triggers apoptosis and autophagy in GC-1 spermatogonia cells.
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  Data: <searchLink fieldCode="AU" term="%22Kim+SG%22">Kim SG</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+DJ%22">Yoon DJ</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Varias+DC%22">Varias DC</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+GJ%22">Ahn GJ</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+GU%22">Han GU</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+SH%22">Moon SH</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HS%22">Lee HS</searchLink>; Department of Food Science and Biotechnology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea; Department of Food Safety and Regulatory Science, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+SH%22">Shin SH</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+BY%22">Ryu BY</searchLink>; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do 17546, Republic of Korea. Electronic address: byryu@cau.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%221301573%22">Pesticide biochemistry and physiology</searchLink> [Pestic Biochem Physiol] 2025 Sep; Vol. 213, pp. 106486. <i>Date of Electronic Publication: </i>2025 Jun 03.
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  Data: Journal Article
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1301573 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9939 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200483575%22">00483575 </searchLink><i>NLM ISO Abbreviation: </i>Pestic Biochem Physiol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.pestbp.2025.106486
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      – Code: eng
        Text: English
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              M: 09
              Text: 2025 Sep
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              Y: 2025
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