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A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging.

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Title: A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging.
Authors: Maccioni L; Department of Information Engineering, University of Padova, Padova, Italy., Brusaferri L; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Computer Science and Informatics, School of Engineering, London South Bank University, London, UK., Barzon L; Department of Information Engineering, University of Padova, Padova, Italy., Schubert JJ; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Nettis MA; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Cousins O; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Rosenzweig I; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Mizuno Y; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; South London and Maudsley NHS Foundation Trust, London, UK.; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan., Vicente-Rodríguez M; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain., Singh N; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Marques TR; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital, Imperial College London, London, UK., Harrison NA; Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK., Fryer T; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Bullmore ET; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Cash D; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Mondelli V; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Pariante C; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Howes O; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, UK., Turkheimer FE; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Loggia ML; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA., Veronese M; Department of Information Engineering, University of Padova, Padova, Italy.; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.
Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2025 Dec; Vol. 45 (12), pp. 2283-2300. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging.
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  Data: <searchLink fieldCode="AU" term="%22Maccioni+L%22">Maccioni L</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Brusaferri+L%22">Brusaferri L</searchLink>; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Computer Science and Informatics, School of Engineering, London South Bank University, London, UK.<br /><searchLink fieldCode="AU" term="%22Barzon+L%22">Barzon L</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Schubert+JJ%22">Schubert JJ</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Nettis+MA%22">Nettis MA</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cousins+O%22">Cousins O</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rosenzweig+I%22">Rosenzweig I</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mizuno+Y%22">Mizuno Y</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; South London and Maudsley NHS Foundation Trust, London, UK.; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Vicente-Rodríguez+M%22">Vicente-Rodríguez M</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Singh+N%22">Singh N</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Marques+TR%22">Marques TR</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+NA%22">Harrison NA</searchLink>; Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Fryer+T%22">Fryer T</searchLink>; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bullmore+ET%22">Bullmore ET</searchLink>; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Cash+D%22">Cash D</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mondelli+V%22">Mondelli V</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pariante+C%22">Pariante C</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Howes+O%22">Howes O</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Turkheimer+FE%22">Turkheimer FE</searchLink>; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Loggia+ML%22">Loggia ML</searchLink>; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Veronese+M%22">Veronese M</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy.; Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.
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  Data: <searchLink fieldCode="JN" term="%228112566%22">Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism</searchLink> [J Cereb Blood Flow Metab] 2025 Dec; Vol. 45 (12), pp. 2283-2300. <i>Date of Electronic Publication: </i>2025 Jul 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8112566 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-7016 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220271678X%22">0271678X </searchLink><i>NLM ISO Abbreviation: </i>J Cereb Blood Flow Metab <i>Subsets: </i>MEDLINE
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