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Formulation and Evaluation of Astaxanthin-Loaded Invasomes as Therapeutic Approaches for Alzheimer's Disease Induced in Rats: Role of SIRT-1/BDNF/miRNA-134/GSK-3β Signaling.

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Title: Formulation and Evaluation of Astaxanthin-Loaded Invasomes as Therapeutic Approaches for Alzheimer's Disease Induced in Rats: Role of SIRT-1/BDNF/miRNA-134/GSK-3β Signaling.
Authors: Kandeil MA; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt., Mohammed ET; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt. eman.ibrahim@vet.bsu.edu.eg., Ibrahim MA; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt., Radi RA; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt., Gamal A; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni‑Suef, Egypt., Abdel-Razik AH; Department of Histopathology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt., Khalil F; Animal and Poultry Management and Wealth Development Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt., Sabry D; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Badr University in Cairo, Cairo, 11829, Egypt.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, 11562, Egypt.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 16189-16208. Date of Electronic Publication: 2025 Aug 01.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Formulation and Evaluation of Astaxanthin-Loaded Invasomes as Therapeutic Approaches for Alzheimer's Disease Induced in Rats: Role of SIRT-1/BDNF/miRNA-134/GSK-3β Signaling.
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  Data: <searchLink fieldCode="AU" term="%22Kandeil+MA%22">Kandeil MA</searchLink>; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohammed+ET%22">Mohammed ET</searchLink>; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt. eman.ibrahim@vet.bsu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Ibrahim+MA%22">Ibrahim MA</searchLink>; Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.<br /><searchLink fieldCode="AU" term="%22Radi+RA%22">Radi RA</searchLink>; Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.<br /><searchLink fieldCode="AU" term="%22Gamal+A%22">Gamal A</searchLink>; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni‑Suef, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdel-Razik+AH%22">Abdel-Razik AH</searchLink>; Department of Histopathology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.<br /><searchLink fieldCode="AU" term="%22Khalil+F%22">Khalil F</searchLink>; Animal and Poultry Management and Wealth Development Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.<br /><searchLink fieldCode="AU" term="%22Sabry+D%22">Sabry D</searchLink>; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Badr University in Cairo, Cairo, 11829, Egypt.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, 11562, Egypt.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Humana+Press%22">Humana Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8900963 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-1182 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208937648%22">08937648 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurobiol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12035-025-05241-5
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        Text: English
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      – TitleFull: Formulation and Evaluation of Astaxanthin-Loaded Invasomes as Therapeutic Approaches for Alzheimer's Disease Induced in Rats: Role of SIRT-1/BDNF/miRNA-134/GSK-3β Signaling.
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              Text: 2025 Dec
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