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Assessing the Safety and Efficacy of Lamotrigine as Anti-myotonic Agent in Myotonic Dystrophy Type 1 (DM1): A Longitudinal, Open-Label, Pilot Study.

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Title: Assessing the Safety and Efficacy of Lamotrigine as Anti-myotonic Agent in Myotonic Dystrophy Type 1 (DM1): A Longitudinal, Open-Label, Pilot Study.
Authors: Risi B; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Ait Allali N; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Cotti Piccinelli S; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Caria F; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Damioli S; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Labella B; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Bertella E; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Giovanelli G; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Garofali F; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Margollicci G; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Carugati R; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy., Ferullo L; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Olivieri E; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Poli L; Unit of Neurology, ASST Spedali Civili, Brescia, Italy., Padovani A; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Filosto M; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy. massimiliano.filosto@unibs.it.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. massimiliano.filosto@unibs.it.
Source: Neurology and therapy [Neurol Ther] 2025 Oct; Vol. 14 (5), pp. 2249-2260. Date of Electronic Publication: 2025 Aug 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: New Zealand NLM ID: 101637818 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8253 (Print) Linking ISSN: 21936536 NLM ISO Abbreviation: Neurol Ther Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Assessing the Safety and Efficacy of Lamotrigine as Anti-myotonic Agent in Myotonic Dystrophy Type 1 (DM1): A Longitudinal, Open-Label, Pilot Study.
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  Data: <searchLink fieldCode="AU" term="%22Risi+B%22">Risi B</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Ait+Allali+N%22">Ait Allali N</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Cotti+Piccinelli+S%22">Cotti Piccinelli S</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Caria+F%22">Caria F</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Damioli+S%22">Damioli S</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Labella+B%22">Labella B</searchLink>; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Bertella+E%22">Bertella E</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Giovanelli+G%22">Giovanelli G</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Garofali+F%22">Garofali F</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Margollicci+G%22">Margollicci G</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Carugati+R%22">Carugati R</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Ferullo+L%22">Ferullo L</searchLink>; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+E%22">Olivieri E</searchLink>; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Poli+L%22">Poli L</searchLink>; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Padovani+A%22">Padovani A</searchLink>; Unit of Neurology, ASST Spedali Civili, Brescia, Italy.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Filosto+M%22">Filosto M</searchLink>; NeMO-Brescia Clinical Center for Neuromuscular Diseases, Brescia, Italy. massimiliano.filosto@unibs.it.; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. massimiliano.filosto@unibs.it.
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  Data: <searchLink fieldCode="JN" term="%22101637818%22">Neurology and therapy</searchLink> [Neurol Ther] 2025 Oct; Vol. 14 (5), pp. 2249-2260. <i>Date of Electronic Publication: </i>2025 Aug 02.
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