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Target-Based Design of Praziquantel Analogs at Cestode TRPMPZQ.

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Title: Target-Based Design of Praziquantel Analogs at Cestode TRPMPZQ.
Authors: Sprague DJ; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Program in Chemical Biology, Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425, United States., Park SK; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Kaethner M; Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Berne, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Berne, Switzerland., Rohr CM; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Ghobrial MR; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Barth DC; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425, United States., Maillard D; Central Process Development - Downstream Processing Services, Merck Electronics KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany., Spangenberg T; Global Health R&D of the Healthcare Business of Merck KGaA, Darmstadt, Germany, Ares Trading S.A. (an affiliate of Merck KGaA, Darmstadt, Germany), 1262 Eysins, Switzerland., Lundström-Stadelmann B; Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Berne, Switzerland.; Multidisciplinary Center for Infectious Diseases, University of Bern, 3012 Berne, Switzerland., Marchant JS; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.
Source: ACS infectious diseases [ACS Infect Dis] 2025 Sep 12; Vol. 11 (9), pp. 2383-2390. Date of Electronic Publication: 2025 Aug 03.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
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  Data: Target-Based Design of Praziquantel Analogs at Cestode TRPM<subscript>PZQ</subscript>.
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  Data: <searchLink fieldCode="AU" term="%22Sprague+DJ%22">Sprague DJ</searchLink>; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Program in Chemical Biology, Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425, United States.<br /><searchLink fieldCode="AU" term="%22Park+SK%22">Park SK</searchLink>; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Kaethner+M%22">Kaethner M</searchLink>; Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Berne, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Berne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rohr+CM%22">Rohr CM</searchLink>; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Ghobrial+MR%22">Ghobrial MR</searchLink>; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.<br /><searchLink fieldCode="AU" term="%22Barth+DC%22">Barth DC</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425, United States.<br /><searchLink fieldCode="AU" term="%22Maillard+D%22">Maillard D</searchLink>; Central Process Development - Downstream Processing Services, Merck Electronics KGaA, Frankfurter Strasse 250, 64293 Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Spangenberg+T%22">Spangenberg T</searchLink>; Global Health R&D of the Healthcare Business of Merck KGaA, Darmstadt, Germany, Ares Trading S.A. (an affiliate of Merck KGaA, Darmstadt, Germany), 1262 Eysins, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lundström-Stadelmann+B%22">Lundström-Stadelmann B</searchLink>; Institute of Parasitology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Berne, Switzerland.; Multidisciplinary Center for Infectious Diseases, University of Bern, 3012 Berne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marchant+JS%22">Marchant JS</searchLink>; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.
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  Data: <searchLink fieldCode="JN" term="%22101654580%22">ACS infectious diseases</searchLink> [ACS Infect Dis] 2025 Sep 12; Vol. 11 (9), pp. 2383-2390. <i>Date of Electronic Publication: </i>2025 Aug 03.
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