Minimum effective dose of a multicomponent behaviour change intervention to increase the physical activity of individuals on primary statin therapy: an adaptive study using the time-to-event continual reassessment method (TiTE-CRM).

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Title: Minimum effective dose of a multicomponent behaviour change intervention to increase the physical activity of individuals on primary statin therapy: an adaptive study using the time-to-event continual reassessment method (TiTE-CRM).
Authors: Goodwin AM; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA agoodwin3@northwell.edu., Friel C; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Miller D; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Vicari F; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Duer-Hefele J; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Chandereng T; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Davidson KW; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA.; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA., Alfano CM; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA., Cheung YK; Mailman School of Public Health, Columbia University Medical Center, New York, New York, USA., Butler MJ; Northwell Health, Feinstein Institutes for Medical Research, Institute of Health System Science, New Hyde Park, New York, USA.
Source: BMJ open [BMJ Open] 2025 Aug 05; Vol. 15 (8), pp. e090789. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Clinical Trial, Phase I; Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2024-090789