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Lanadelumab's impact on hereditary angioedema control and quality of life across disease activity subgroups: Real-world evidence.

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Title: Lanadelumab's impact on hereditary angioedema control and quality of life across disease activity subgroups: Real-world evidence.
Authors: Zanichelli A; Operative Unit of Medicine, Angioedema Center, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Donato, San Donato Milanese, Milan, Italy; Dipartimento di Scienze Biomediche per la Salute, University of Milan, Milan, Italy., Wuillemin WA; Division of Hematology and Hematology Laboratory, Department of Internal Medicine, Luzerner Kantonsspital, Lucerne and University of Berne, Berne, Switzerland., Aygören-Pürsün E; Department for Children and Adolescents, Angioedema Centre, University Hospital Frankfurt, Goethe University, Frankfurt, Germany., Banerji A; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Busse PJ; Division of Allergy and Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, New York., Betschel SD; Division of Clinical Immunology and Allergy, University of Toronto, Toronto, Ontario, Canada., Cancian M; Department of Systems Medicine, University Hospital of Padua, Padua, Italy., Gagnon R; Laval University, Centre Hospitalier Universitaire de Québec (CHUL), Québec, Canada., Goodyear MD; Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Kinaciyan T; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Kessel A; Division of Allergy and Clinical Immunology, Bnai Zion Medical Centre, Technion Faculty of Medicine, Haifa, Israel., Magerl M; Institute of Allergology, Charité-Universitätsmedizin Berlin (corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin), Berlin, Germany; Immunology and Allergology, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Immunology and Allergology, Berlin, Germany., Recke A; Department of Dermatology, Allergology and Venereology, University of Lübeck, Lübeck, Germany., Wedner HJ; Division of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Estepan DN; Takeda Development Center Americas, Inc, Lexington, Massachusetts. Electronic address: daniel.novaestepan@takeda.com., Watt M; Takeda Development Center Americas, Inc, Lexington, Massachusetts., Andresen I; Takeda Pharmaceuticals International Aktiengesellschaft (AG), Zurich, Switzerland., Juethner S; Takeda Pharmaceuticals USA, Inc., Lexington, Massachusetts., Khutoryansky N; Takeda Development Center Americas, Inc, Lexington, Massachusetts., Martinez-Saguer I; Hämophilie-Zentrum Rhein Main (HZRM), Frankfurt/Main, Germany.
Source: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2025 Nov; Vol. 135 (5), pp. 560-569.e2. Date of Electronic Publication: 2025 Sep 06.
Publication Type: Clinical Trial, Phase IV; Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: American College of Allergy, Asthma, and Immunology Country of Publication: United States NLM ID: 9503580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4436 (Electronic) Linking ISSN: 10811206 NLM ISO Abbreviation: Ann Allergy Asthma Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lanadelumab's impact on hereditary angioedema control and quality of life across disease activity subgroups: Real-world evidence.
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  Data: <searchLink fieldCode="AU" term="%22Zanichelli+A%22">Zanichelli A</searchLink>; Operative Unit of Medicine, Angioedema Center, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Donato, San Donato Milanese, Milan, Italy; Dipartimento di Scienze Biomediche per la Salute, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Wuillemin+WA%22">Wuillemin WA</searchLink>; Division of Hematology and Hematology Laboratory, Department of Internal Medicine, Luzerner Kantonsspital, Lucerne and University of Berne, Berne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Aygören-Pürsün+E%22">Aygören-Pürsün E</searchLink>; Department for Children and Adolescents, Angioedema Centre, University Hospital Frankfurt, Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Banerji+A%22">Banerji A</searchLink>; Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Busse+PJ%22">Busse PJ</searchLink>; Division of Allergy and Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Betschel+SD%22">Betschel SD</searchLink>; Division of Clinical Immunology and Allergy, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Cancian+M%22">Cancian M</searchLink>; Department of Systems Medicine, University Hospital of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Gagnon+R%22">Gagnon R</searchLink>; Laval University, Centre Hospitalier Universitaire de Québec (CHUL), Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Goodyear+MD%22">Goodyear MD</searchLink>; Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Kinaciyan+T%22">Kinaciyan T</searchLink>; Department of Dermatology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kessel+A%22">Kessel A</searchLink>; Division of Allergy and Clinical Immunology, Bnai Zion Medical Centre, Technion Faculty of Medicine, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Magerl+M%22">Magerl M</searchLink>; Institute of Allergology, Charité-Universitätsmedizin Berlin (corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin), Berlin, Germany; Immunology and Allergology, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Immunology and Allergology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Recke+A%22">Recke A</searchLink>; Department of Dermatology, Allergology and Venereology, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Wedner+HJ%22">Wedner HJ</searchLink>; Division of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Estepan+DN%22">Estepan DN</searchLink>; Takeda Development Center Americas, Inc, Lexington, Massachusetts. Electronic address: daniel.novaestepan@takeda.com.<br /><searchLink fieldCode="AU" term="%22Watt+M%22">Watt M</searchLink>; Takeda Development Center Americas, Inc, Lexington, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Andresen+I%22">Andresen I</searchLink>; Takeda Pharmaceuticals International Aktiengesellschaft (AG), Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Juethner+S%22">Juethner S</searchLink>; Takeda Pharmaceuticals USA, Inc., Lexington, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Khutoryansky+N%22">Khutoryansky N</searchLink>; Takeda Development Center Americas, Inc, Lexington, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Martinez-Saguer+I%22">Martinez-Saguer I</searchLink>; Hämophilie-Zentrum Rhein Main (HZRM), Frankfurt/Main, Germany.
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  Data: <searchLink fieldCode="JN" term="%229503580%22">Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology</searchLink> [Ann Allergy Asthma Immunol] 2025 Nov; Vol. 135 (5), pp. 560-569.e2. <i>Date of Electronic Publication: </i>2025 Sep 06.
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