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Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease.

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Title: Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease.
Authors: Blair GW; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Department of Stroke and Medicine for the Elderly, Royal Infirmary Edinburgh, UK., MacCormick IJC; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; Institute for Adaptive and Neural Computation, University of Edinburgh, UK., McGrory S; Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, UK., MacGillivray T; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Hamilton I; Edinburgh Imaging, University of Edinburgh, UK., Shi Y; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Chappell F; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Thrippleton MJ; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Stringer MS; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Doubal F; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK., Wardlaw JM; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.
Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2025 Dec; Vol. 45 (12), pp. 2301-2315. Date of Electronic Publication: 2025 Aug 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Retinal vascular reactivity is associated with white matter hyperintensities and dysfunctional cerebrovascular reactivity in cerebral small vessel disease.
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  Data: <searchLink fieldCode="AU" term="%22Blair+GW%22">Blair GW</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Department of Stroke and Medicine for the Elderly, Royal Infirmary Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22MacCormick+IJC%22">MacCormick IJC</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; Institute for Adaptive and Neural Computation, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22McGrory+S%22">McGrory S</searchLink>; Department of Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22MacGillivray+T%22">MacGillivray T</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Hamilton+I%22">Hamilton I</searchLink>; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Chappell+F%22">Chappell F</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Thrippleton+MJ%22">Thrippleton MJ</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Stringer+MS%22">Stringer MS</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Doubal+F%22">Doubal F</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Wardlaw+JM%22">Wardlaw JM</searchLink>; Centre for Clinical Brain Sciences, University of Edinburgh, UK.; Row Fogo Centre for Research into Ageing and the Brain, University of Edinburgh, UK.; UK Dementia Research Institute Centre, University of Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, UK.
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              M: 12
              Text: 2025 Dec
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