Paired single-cell and spatial transcriptional profiling reveals a central osteopontin macrophage response mediating tuberculous granuloma formation.
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| Title: | Paired single-cell and spatial transcriptional profiling reveals a central osteopontin macrophage response mediating tuberculous granuloma formation. |
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| Authors: | Pyle CJ; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA., Wang L; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Beerman RW; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Jain V; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, USA., Ohman HKE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA., Thompson BA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA., Abramson KR; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, USA., Ko DC; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Gregory SG; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, USA., Smith CM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA., Neff JL; Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA., Richardson RJ; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom., Stout JE; Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA., Tobin DM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA. |
| Source: | MBio [mBio] 2025 Sep 10; Vol. 16 (9), pp. e0155925. Date of Electronic Publication: 2025 Aug 07. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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