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Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice.

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Title: Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice.
Authors: Hoyt LR; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Liu E; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Section of Rheumatology, Allergy & Immunology, Yale University School of Medicine, New Haven, CT, USA., Olson EC; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Jacobsen DR; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Siniscalco ER; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Krier-Burris RA; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Greenfield KG; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., McBride CD; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Alfajaro MM; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Amat JAR; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Zhao Z; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Xu L; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Philip V; The Jackson Laboratory, Bar Harbor, ME, USA., Verma A; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Fourati S; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Senger DL; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, PQ, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, PQ, Canada., Zhang L; Department of Genetics & Genomic Sciences, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bunyavanich S; Department of Genetics & Genomic Sciences, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Glass SE; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Coffey RJ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Wilen CB; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., Williams A; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Eisenbarth SC; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Source: Science (New York, N.Y.) [Science] 2025 Aug 07; Vol. 389 (6760), pp. eadp0240. Date of Electronic Publication: 2025 Aug 07.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice.
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  Data: <searchLink fieldCode="AU" term="%22Hoyt+LR%22">Hoyt LR</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Liu+E%22">Liu E</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Section of Rheumatology, Allergy & Immunology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Olson+EC%22">Olson EC</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Jacobsen+DR%22">Jacobsen DR</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Siniscalco+ER%22">Siniscalco ER</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Krier-Burris+RA%22">Krier-Burris RA</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Greenfield+KG%22">Greenfield KG</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22McBride+CD%22">McBride CD</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Alfajaro+MM%22">Alfajaro MM</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Amat+JAR%22">Amat JAR</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Philip+V%22">Philip V</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Verma+A%22">Verma A</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Fourati+S%22">Fourati S</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Senger+DL%22">Senger DL</searchLink>; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, PQ, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, PQ, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Genetics & Genomic Sciences, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bunyavanich+S%22">Bunyavanich S</searchLink>; Department of Genetics & Genomic Sciences, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Glass+SE%22">Glass SE</searchLink>; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Coffey+RJ%22">Coffey RJ</searchLink>; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wilen+CB%22">Wilen CB</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Williams+A%22">Williams A</searchLink>; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Eisenbarth+SC%22">Eisenbarth SC</searchLink>; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA.; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; The Department Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Human Immunobiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
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  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2025 Aug 07; Vol. 389 (6760), pp. eadp0240. <i>Date of Electronic Publication: </i>2025 Aug 07.
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