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An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut.

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Title: An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut.
Authors: Xu RJ; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Cadinu P; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Nicol PB; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Herrmann US; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Lee T; Core for Computational Biomedicine, Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Geistlinger L; Core for Computational Biomedicine, Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Irizarry RA; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Moffitt JR; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Lead contact.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jul 24. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut.
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  Data: <searchLink fieldCode="AU" term="%22Xu+RJ%22">Xu RJ</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Cadinu+P%22">Cadinu P</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Nicol+PB%22">Nicol PB</searchLink>; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Herrmann+US%22">Herrmann US</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lee+T%22">Lee T</searchLink>; Core for Computational Biomedicine, Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Geistlinger+L%22">Geistlinger L</searchLink>; Core for Computational Biomedicine, Department of Biomedical Informatics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Irizarry+RA%22">Irizarry RA</searchLink>; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Moffitt+JR%22">Moffitt JR</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA.; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.; Lead contact.
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        Value: 10.1101/2025.07.21.665958
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        Text: English
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              Text: 2025 Jul 24
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