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Structural Insights: What Makes Some PDE4 Inhibitors More Effective in Inflammatory Dermatoses.

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Title: Structural Insights: What Makes Some PDE4 Inhibitors More Effective in Inflammatory Dermatoses.
Authors: Issa NT; Dr. Issa is with Forefront Dermatology in Vienna, Virginia; the University of Miami Miller School of Medicine in Miami, Florida; the Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery in Miami, Florida; and the Department of Dermatology at George Washington University School of Medicine and Health Sciences in Washington, District of Columbia., Wang J; Drs. Wang and Bunick are with the Department of Molecular Biophysics and Biochemistry at Yale University in New Haven, Connecticut., Hanly A; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut., Ho M; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut., Obagi S; Ms. Obagi is with the College of Medicine at the University of Arizona in Tucson, Arizona., Damiani G; Dr. Damiani is with the Department of Biomedical, Surgical, and Dental Sciences at the University of Milan in Milan, Italy; and Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico in Milan, Italy., Del Rosso JQ; Dr. Del Rosso is with JDR Dermatology Research in Las Vegas, Nevada; Advanced Dermatology and Cosmetic Surgery in Maitland, Florida; and the Department of Dermatology at Touro University Nevada in Henderson, Nevada., Kang Y; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.; Dr. Kang is with Yale-New Haven Hospital Pharmacy in New Haven, Connecticut., Bunick CG; Drs. Wang and Bunick are with the Department of Molecular Biophysics and Biochemistry at Yale University in New Haven, Connecticut.; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.; Dr. Bunick is also with the Program in Translational Biomedicine at Yale School of Medicine in New Haven, Connecticut.
Source: The Journal of clinical and aesthetic dermatology [J Clin Aesthet Dermatol] 2025 Jul 01; Vol. 18 (7), pp. 18-21.
Publication Type: Journal Article; Review
Journal Info: Publisher: Matrix Medical Communications Country of Publication: United States NLM ID: 101518173 Publication Model: Print Cited Medium: Print ISSN: 1941-2789 (Print) Linking ISSN: 19412789 NLM ISO Abbreviation: J Clin Aesthet Dermatol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural Insights: What Makes Some PDE4 Inhibitors More Effective in Inflammatory Dermatoses.
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  Data: <searchLink fieldCode="AU" term="%22Issa+NT%22">Issa NT</searchLink>; Dr. Issa is with Forefront Dermatology in Vienna, Virginia; the University of Miami Miller School of Medicine in Miami, Florida; the Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery in Miami, Florida; and the Department of Dermatology at George Washington University School of Medicine and Health Sciences in Washington, District of Columbia.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Drs. Wang and Bunick are with the Department of Molecular Biophysics and Biochemistry at Yale University in New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Hanly+A%22">Hanly A</searchLink>; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Ho+M%22">Ho M</searchLink>; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Obagi+S%22">Obagi S</searchLink>; Ms. Obagi is with the College of Medicine at the University of Arizona in Tucson, Arizona.<br /><searchLink fieldCode="AU" term="%22Damiani+G%22">Damiani G</searchLink>; Dr. Damiani is with the Department of Biomedical, Surgical, and Dental Sciences at the University of Milan in Milan, Italy; and Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico in Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Rosso+JQ%22">Del Rosso JQ</searchLink>; Dr. Del Rosso is with JDR Dermatology Research in Las Vegas, Nevada; Advanced Dermatology and Cosmetic Surgery in Maitland, Florida; and the Department of Dermatology at Touro University Nevada in Henderson, Nevada.<br /><searchLink fieldCode="AU" term="%22Kang+Y%22">Kang Y</searchLink>; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.; Dr. Kang is with Yale-New Haven Hospital Pharmacy in New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Bunick+CG%22">Bunick CG</searchLink>; Drs. Wang and Bunick are with the Department of Molecular Biophysics and Biochemistry at Yale University in New Haven, Connecticut.; Drs. Bunick, Kang, Hanly, and Mr. Ho are with the Department of Dermatology at Yale School of Medicine in New Haven, Connecticut.; Dr. Bunick is also with the Program in Translational Biomedicine at Yale School of Medicine in New Haven, Connecticut.
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  Data: <searchLink fieldCode="JN" term="%22101518173%22">The Journal of clinical and aesthetic dermatology</searchLink> [J Clin Aesthet Dermatol] 2025 Jul 01; Vol. 18 (7), pp. 18-21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Matrix+Medical+Communications%22">Matrix Medical Communications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101518173 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>1941-2789 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219412789%22">19412789 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Aesthet Dermatol <i>Subsets: </i>PubMed not MEDLINE
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              M: 07
              Text: 2025 Jul 01
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