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Real-time monitoring of attenuated cytomegalovirus using Raman spectroscopy allows non-destructive characterization during flow.

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Title: Real-time monitoring of attenuated cytomegalovirus using Raman spectroscopy allows non-destructive characterization during flow.
Authors: Athalye SM; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA., Maruthamuthu MK; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA., Esmaili E; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA., Boodaghidizaji M; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA., Sarathy N; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Computer Science, Purdue University, West Lafayette, IN 47907, USA., Mayorga C; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA., Raffaele J; Analytical Research and Development, Merck & Co., Inc., West Point, PA 19486, USA., Selvamani V; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; School of Material Science Engineering, Purdue University, West Lafayette, IN 47907, USA., Smith JP; Process Research and Development, MRL, Merck & Co., Inc., West Point, PA 19486, USA., Matos T; Bioprocess Drug Substance & Commercialization, Merck & Co., Inc., Kenilworth, NJ 07033, USA., Rustandi RR; Analytical Research and Development, Merck & Co., Inc., West Point, PA 19486, USA., Ardekani AM; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: ardekani@purdue.edu., Verma MS; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: msverma@purdue.edu.
Source: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2026 Jan 15; Vol. 345, pp. 126761. Date of Electronic Publication: 2025 Aug 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Athalye+SM%22">Athalye SM</searchLink>; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Maruthamuthu+MK%22">Maruthamuthu MK</searchLink>; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Esmaili+E%22">Esmaili E</searchLink>; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Boodaghidizaji+M%22">Boodaghidizaji M</searchLink>; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Sarathy+N%22">Sarathy N</searchLink>; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Computer Science, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Mayorga+C%22">Mayorga C</searchLink>; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Raffaele+J%22">Raffaele J</searchLink>; Analytical Research and Development, Merck & Co., Inc., West Point, PA 19486, USA.<br /><searchLink fieldCode="AU" term="%22Selvamani+V%22">Selvamani V</searchLink>; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; School of Material Science Engineering, Purdue University, West Lafayette, IN 47907, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JP%22">Smith JP</searchLink>; Process Research and Development, MRL, Merck & Co., Inc., West Point, PA 19486, USA.<br /><searchLink fieldCode="AU" term="%22Matos+T%22">Matos T</searchLink>; Bioprocess Drug Substance & Commercialization, Merck & Co., Inc., Kenilworth, NJ 07033, USA.<br /><searchLink fieldCode="AU" term="%22Rustandi+RR%22">Rustandi RR</searchLink>; Analytical Research and Development, Merck & Co., Inc., West Point, PA 19486, USA.<br /><searchLink fieldCode="AU" term="%22Ardekani+AM%22">Ardekani AM</searchLink>; School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: ardekani@purdue.edu.<br /><searchLink fieldCode="AU" term="%22Verma+MS%22">Verma MS</searchLink>; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, USA; Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. Electronic address: msverma@purdue.edu.
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              Text: 2026 Jan 15
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