A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults.

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Title: A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults.
Authors: Schultz JL; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Division of Pharmacy Practice and Sciences, College of Pharmacy, University of Iowa, Iowa City, IA, USA., Gander PE; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Workman CD; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Boles Ponto LL; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Cross S; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Nance CS; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Groth CL; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Taylor EB; Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Ernst SE; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA., Xu J; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Uc EY; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Veteran's Affairs Medical Center, Iowa City, IA, USA., Magnotta VA; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Welsh MJ; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA., Narayanan NS; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Source: Journal of Parkinson's disease [J Parkinsons Dis] 2025 Nov; Vol. 15 (7), pp. 1253-1263. Date of Electronic Publication: 2025 Aug 10.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101567362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-718X (Electronic) Linking ISSN: 18777171 NLM ISO Abbreviation: J Parkinsons Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Schultz+JL%22">Schultz JL</searchLink>; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Division of Pharmacy Practice and Sciences, College of Pharmacy, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Gander+PE%22">Gander PE</searchLink>; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Workman+CD%22">Workman CD</searchLink>; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Boles+Ponto+LL%22">Boles Ponto LL</searchLink>; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Cross+S%22">Cross S</searchLink>; Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Nance+CS%22">Nance CS</searchLink>; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Groth+CL%22">Groth CL</searchLink>; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+EB%22">Taylor EB</searchLink>; Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Ernst+SE%22">Ernst SE</searchLink>; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Uc+EY%22">Uc EY</searchLink>; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Veteran's Affairs Medical Center, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Magnotta+VA%22">Magnotta VA</searchLink>; Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Welsh+MJ%22">Welsh MJ</searchLink>; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Narayanan+NS%22">Narayanan NS</searchLink>; Department of Neurology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Pappajohn Biomedical Institute, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101567362 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1877-718X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218777171%22">18777171 </searchLink><i>NLM ISO Abbreviation: </i>J Parkinsons Dis <i>Subsets: </i>MEDLINE
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