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Nivolumab plus cabozantinib in metastatic renal cell carcinoma: real-world evidence from the international ARON-1 study.

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Title: Nivolumab plus cabozantinib in metastatic renal cell carcinoma: real-world evidence from the international ARON-1 study.
Authors: Bourlon MT; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.; Escuela de Medicina, Universidad Panamericana, Mexico City, Mexico., Galli L; Oncology Unit 2, University Hospital of Pisa, Pisa, Italy., Grande E; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain., Park SH; Department of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Melichar B; Department of Oncology, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czechia., Schieber TJ; Division of Medical Oncology, Department of Internal Medicine, University of Kansas Cancer Center, Westwood, KS, United States., Juan-Fita MJ; Department of Medical Oncology, Fundacion Instituto Valenciano de Oncologia, Valencia, Spain., Ürün Y; Department of Medical Oncology, Ankara University Faculty of Medicine, Ankara, Türkiye., Molina-Cerrillo J; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., Alonso-Gordoa T; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain., De Giorgi U; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Kucharz J; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Warsaw, Poland., Pérez Calabuig E; Medical Oncology Department, CHU Insular-Materno Infantil, Las Palmas de Gran Canaria, Spain., Conteduca V; Unit of Medical Oncology and Biomolecular Therapy and C.R.E.A.T.E - Center for Research and Innovation Medicine, Department of Medical and Surgical Sciences, University of Foggia, Policlinico Riuniti, Foggia, Italy., Taha T; The Institute of Cancer Research, London, United Kingdom.; Royal Marsden NHS Foundation Trust, London, United Kingdom., Rescigno P; Translational and Clinical Research Institute, Centre for Cancer, Newcastle University, Newcastle upon Tyne, United Kingdom., Abu-Sini H; Oncology Institute, Haifa, Israel., Spinelli GP; UOC Oncologia Territoriale Ausl Latina, Aprilia, Italy., Manneh Kopp R; Clinical Oncology, Sociedad de Oncología y Hematología del Cesar, Valledupar, Colombia., Salfi A; Oncology Unit 2, University Hospital of Pisa, Pisa, Italy., Bhuva D; Department of Medical Oncology, Army Hospital Research and Referral, New Delhi, India., Valdez-Sandoval P; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico., Mendez-Bribiesca S; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico., Fiala O; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czechia.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia., Buti S; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.; Department of Medicine and Surgery, University of Parma, Parma, Italy., Marques Monteiro FS; Genitourinary Cancer Group, Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil., Bamias A; 2nd Propaedeutic Department of Internal Medicine, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Ghosn M; Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon., Massari F; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy., Ansari J; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates., Santoni M; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
Source: Frontiers in oncology [Front Oncol] 2025 Jul 25; Vol. 15, pp. 1605282. Date of Electronic Publication: 2025 Jul 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
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  Data: Nivolumab plus cabozantinib in metastatic renal cell carcinoma: real-world evidence from the international ARON-1 study.
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  Data: <searchLink fieldCode="AU" term="%22Bourlon+MT%22">Bourlon MT</searchLink>; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.; Escuela de Medicina, Universidad Panamericana, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Galli+L%22">Galli L</searchLink>; Oncology Unit 2, University Hospital of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Grande+E%22">Grande E</searchLink>; Department of Medical Oncology, MD Anderson Cancer Center Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Park+SH%22">Park SH</searchLink>; Department of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Melichar+B%22">Melichar B</searchLink>; Department of Oncology, Faculty of Medicine and Dentistry, Palacký University, Olomouc, Czechia.<br /><searchLink fieldCode="AU" term="%22Schieber+TJ%22">Schieber TJ</searchLink>; Division of Medical Oncology, Department of Internal Medicine, University of Kansas Cancer Center, Westwood, KS, United States.<br /><searchLink fieldCode="AU" term="%22Juan-Fita+MJ%22">Juan-Fita MJ</searchLink>; Department of Medical Oncology, Fundacion Instituto Valenciano de Oncologia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Ürün+Y%22">Ürün Y</searchLink>; Department of Medical Oncology, Ankara University Faculty of Medicine, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Molina-Cerrillo+J%22">Molina-Cerrillo J</searchLink>; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso-Gordoa+T%22">Alonso-Gordoa T</searchLink>; Department of Medical Oncology, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22De+Giorgi+U%22">De Giorgi U</searchLink>; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Kucharz+J%22">Kucharz J</searchLink>; Department of Uro-Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Pérez+Calabuig+E%22">Pérez Calabuig E</searchLink>; Medical Oncology Department, CHU Insular-Materno Infantil, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Conteduca+V%22">Conteduca V</searchLink>; Unit of Medical Oncology and Biomolecular Therapy and C.R.E.A.T.E - Center for Research and Innovation Medicine, Department of Medical and Surgical Sciences, University of Foggia, Policlinico Riuniti, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Taha+T%22">Taha T</searchLink>; The Institute of Cancer Research, London, United Kingdom.; Royal Marsden NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rescigno+P%22">Rescigno P</searchLink>; Translational and Clinical Research Institute, Centre for Cancer, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Abu-Sini+H%22">Abu-Sini H</searchLink>; Oncology Institute, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Spinelli+GP%22">Spinelli GP</searchLink>; UOC Oncologia Territoriale Ausl Latina, Aprilia, Italy.<br /><searchLink fieldCode="AU" term="%22Manneh+Kopp+R%22">Manneh Kopp R</searchLink>; Clinical Oncology, Sociedad de Oncología y Hematología del Cesar, Valledupar, Colombia.<br /><searchLink fieldCode="AU" term="%22Salfi+A%22">Salfi A</searchLink>; Oncology Unit 2, University Hospital of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Bhuva+D%22">Bhuva D</searchLink>; Department of Medical Oncology, Army Hospital Research and Referral, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Valdez-Sandoval+P%22">Valdez-Sandoval P</searchLink>; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Mendez-Bribiesca+S%22">Mendez-Bribiesca S</searchLink>; Department of Hemato-Oncology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Fiala+O%22">Fiala O</searchLink>; Department of Oncology and Radiotherapeutics, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czechia.; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czechia.<br /><searchLink fieldCode="AU" term="%22Buti+S%22">Buti S</searchLink>; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.; Department of Medicine and Surgery, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Marques+Monteiro+FS%22">Marques Monteiro FS</searchLink>; Genitourinary Cancer Group, Latin American Cooperative Oncology Group - LACOG, Porto Alegre, Brazil.; Oncology and Hematology Department, Hospital Sírio Libanês, Brasília, Brazil.<br /><searchLink fieldCode="AU" term="%22Bamias+A%22">Bamias A</searchLink>; 2nd Propaedeutic Department of Internal Medicine, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Ghosn+M%22">Ghosn M</searchLink>; Hematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Beirut, Lebanon.<br /><searchLink fieldCode="AU" term="%22Massari+F%22">Massari F</searchLink>; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ansari+J%22">Ansari J</searchLink>; Medical Oncology, Tawam Hospital, Al Ain, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Santoni+M%22">Santoni M</searchLink>; Medical Oncology Unit, Macerata Hospital, Macerata, Italy.
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