More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles.

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Title: More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles.
Authors: Jarchow M; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA., Driscoll I; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA., Breidenbach BM; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA., Cook N; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; NeuroGenomics and Informatics Center Washington University School of Medicine St. Louis Missouri USA., Gallagher CL; Geriatric Research Education and Clinical Center William S. Middleton VA Hospital Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA., Johnson SC; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA., Asthana S; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Geriatric Research Education and Clinical Center William S. Middleton VA Hospital Madison Wisconsin USA., Hermann BP; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA., Sager MA; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA., Blennow K; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Paris Brain Institute ICM, Pitié-Salpêtrière Hospital Sorbonne University Paris France.; Neurodegenerative Disorder Research Center Division of Life Sciences and Medicine and Department of Neurology Institute on Aging and Brain Disorders University of Science and Technology of China and First Affiliated Hospital of USTC Hefei China., Zetterberg H; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK.; Hong Kong Center for Neurodegenerative Diseases Clear Water Bay Hong Kong China.; Roche Diagnostics GmbH Penzberg Germany., Carlsson CM; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA., Kollmorgen G; Roche Diagnostics GmbH Penzberg Germany., Quijano-Rubio C; Roche Diagnostics International Ltd Rotkreuz Switzerland., Cook DB; Research Service William S. Middleton VA Hospital Madison Wisconsin USA.; Department of Kinesiology School of Education University of Wisconsin-Madison Madison Wisconsin USA., Dubal DB; Department of Neurology and Weill Institute for Neurosciences University of California San Francisco California USA., Okonkwo OC; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.
Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2025 Aug 08; Vol. 11 (3), pp. e70133. Date of Electronic Publication: 2025 Aug 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE
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  Data: More fit KL-VS heterozygotes have more favorable AD-relevant biomarker profiles.
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  Data: <searchLink fieldCode="AU" term="%22Jarchow+M%22">Jarchow M</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Driscoll+I%22">Driscoll I</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Breidenbach+BM%22">Breidenbach BM</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Cook+N%22">Cook N</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; NeuroGenomics and Informatics Center Washington University School of Medicine St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Gallagher+CL%22">Gallagher CL</searchLink>; Geriatric Research Education and Clinical Center William S. Middleton VA Hospital Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Johnson+SC%22">Johnson SC</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Asthana+S%22">Asthana S</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Geriatric Research Education and Clinical Center William S. Middleton VA Hospital Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Hermann+BP%22">Hermann BP</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Sager+MA%22">Sager MA</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Paris Brain Institute ICM, Pitié-Salpêtrière Hospital Sorbonne University Paris France.; Neurodegenerative Disorder Research Center Division of Life Sciences and Medicine and Department of Neurology Institute on Aging and Brain Disorders University of Science and Technology of China and First Affiliated Hospital of USTC Hefei China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden.; Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden.; Department of Neurodegenerative Disease UCL Institute of Neurology London UK.; UK Dementia Research Institute at UCL London UK.; Hong Kong Center for Neurodegenerative Diseases Clear Water Bay Hong Kong China.; Roche Diagnostics GmbH Penzberg Germany.<br /><searchLink fieldCode="AU" term="%22Carlsson+CM%22">Carlsson CM</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.; Department of Neurology School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Kollmorgen+G%22">Kollmorgen G</searchLink>; Roche Diagnostics GmbH Penzberg Germany.<br /><searchLink fieldCode="AU" term="%22Quijano-Rubio+C%22">Quijano-Rubio C</searchLink>; Roche Diagnostics International Ltd Rotkreuz Switzerland.<br /><searchLink fieldCode="AU" term="%22Cook+DB%22">Cook DB</searchLink>; Research Service William S. Middleton VA Hospital Madison Wisconsin USA.; Department of Kinesiology School of Education University of Wisconsin-Madison Madison Wisconsin USA.<br /><searchLink fieldCode="AU" term="%22Dubal+DB%22">Dubal DB</searchLink>; Department of Neurology and Weill Institute for Neurosciences University of California San Francisco California USA.<br /><searchLink fieldCode="AU" term="%22Okonkwo+OC%22">Okonkwo OC</searchLink>; Wisconsin Alzheimer's Disease Research Center Department of Medicine School of Medicine and Public Health University of Wisconsin-Madison Madison Wisconsin USA.; Wisconsin Alzheimer's Institute Madison Wisconsin USA.
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  Data: <searchLink fieldCode="JN" term="%22101650118%22">Alzheimer's & dementia (New York, N. Y.)</searchLink> [Alzheimers Dement (N Y)] 2025 Aug 08; Vol. 11 (3), pp. e70133. <i>Date of Electronic Publication: </i>2025 Aug 08 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101650118 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-8737 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528737%22">23528737 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (N Y) <i>Subsets: </i>PubMed not MEDLINE
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