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Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results.

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Title: Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results.
Authors: Wainberg ZA; University of California, Los Angeles, Los Angeles, CA, USA. zwainberg@mednet.ucla.edu., Weekes CD; Massachusetts General Hospital, Boston, MA, USA., Furqan M; University of Iowa, Iowa City, IA, USA., Kasi PM; University of Iowa, Iowa City, IA, USA., Devoe CE; Northwell Health, Lake Success, NY, USA., Leal AD; University of Colorado School of Medicine, Aurora, CO, USA., Chung V; City of Hope, Duarte, CA, USA., Perry JR; Elicio Therapeutics, Boston, MA, USA., Kheoh T; Elicio Therapeutics, Boston, MA, USA., McNeil LK; Elicio Therapeutics, Boston, MA, USA., Welkowsky E; Elicio Therapeutics, Boston, MA, USA., DeMuth PC; Elicio Therapeutics, Boston, MA, USA., Haqq CM; Elicio Therapeutics, Boston, MA, USA. chris.haqq@elicio.com., Pant S; University of Texas MD Anderson Cancer Center, Houston, TX, USA. spant@mdanderson.org., O'Reilly EM; Memorial Sloan Kettering Cancer Center, New York City, NY, USA. oreillye@mskcc.org.
Source: Nature medicine [Nat Med] 2025 Nov; Vol. 31 (11), pp. 3648-3653. Date of Electronic Publication: 2025 Aug 11.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results.
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  Data: <searchLink fieldCode="AU" term="%22Wainberg+ZA%22">Wainberg ZA</searchLink>; University of California, Los Angeles, Los Angeles, CA, USA. zwainberg@mednet.ucla.edu.<br /><searchLink fieldCode="AU" term="%22Weekes+CD%22">Weekes CD</searchLink>; Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Furqan+M%22">Furqan M</searchLink>; University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Kasi+PM%22">Kasi PM</searchLink>; University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Devoe+CE%22">Devoe CE</searchLink>; Northwell Health, Lake Success, NY, USA.<br /><searchLink fieldCode="AU" term="%22Leal+AD%22">Leal AD</searchLink>; University of Colorado School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Chung+V%22">Chung V</searchLink>; City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Perry+JR%22">Perry JR</searchLink>; Elicio Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kheoh+T%22">Kheoh T</searchLink>; Elicio Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McNeil+LK%22">McNeil LK</searchLink>; Elicio Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Welkowsky+E%22">Welkowsky E</searchLink>; Elicio Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22DeMuth+PC%22">DeMuth PC</searchLink>; Elicio Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Haqq+CM%22">Haqq CM</searchLink>; Elicio Therapeutics, Boston, MA, USA. chris.haqq@elicio.com.<br /><searchLink fieldCode="AU" term="%22Pant+S%22">Pant S</searchLink>; University of Texas MD Anderson Cancer Center, Houston, TX, USA. spant@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22O'Reilly+EM%22">O'Reilly EM</searchLink>; Memorial Sloan Kettering Cancer Center, New York City, NY, USA. oreillye@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2025 Nov; Vol. 31 (11), pp. 3648-3653. <i>Date of Electronic Publication: </i>2025 Aug 11.
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