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Development and Validation of a LC-MS/MS Method for Ripretinib and Its Metabolite: Example of a Journey From Laboratory Bench to Routine Application With a Greenness Assessment.

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Title: Development and Validation of a LC-MS/MS Method for Ripretinib and Its Metabolite: Example of a Journey From Laboratory Bench to Routine Application With a Greenness Assessment.
Authors: Rakotovao C; Department of Pharmacy, CHU Bordeaux, Pessac, France.; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France., Sharanek A; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France., Burban A; IBGC, UMR5095, Univ. Bordeaux, CNRS, Bordeaux, France., Gueroue P; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France., Bouchet S; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; BPH, UMR1219, Univ. Bordeaux, INSERM, Bordeaux, France., Bouguéon G; Department of Pharmacy, CHU Bordeaux, Pessac, France.; ARNA Laboratory, UMR1212, CNRS, ChemBioPharm, UMR5320, Univ. Bordeaux, INSERM, Bordeaux, France., Ducint D; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France., Molimard M; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; BPH, UMR1219, Univ. Bordeaux, INSERM, Bordeaux, France., Italiano A; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.; Bergonie Institut, CLCC, Bordeaux, France., Djabarouti S; Department of Pharmacy, CHU Bordeaux, Pessac, France.; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France., Guyon J; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; Department of Biochemistry, CHU Bordeaux, Bordeaux, France.
Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Sep; Vol. 39 (9), pp. e70190.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Rakotovao+C%22">Rakotovao C</searchLink>; Department of Pharmacy, CHU Bordeaux, Pessac, France.; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Sharanek+A%22">Sharanek A</searchLink>; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Burban+A%22">Burban A</searchLink>; IBGC, UMR5095, Univ. Bordeaux, CNRS, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Gueroue+P%22">Gueroue P</searchLink>; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Bouchet+S%22">Bouchet S</searchLink>; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; BPH, UMR1219, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Bouguéon+G%22">Bouguéon G</searchLink>; Department of Pharmacy, CHU Bordeaux, Pessac, France.; ARNA Laboratory, UMR1212, CNRS, ChemBioPharm, UMR5320, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Ducint+D%22">Ducint D</searchLink>; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Molimard+M%22">Molimard M</searchLink>; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; BPH, UMR1219, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Italiano+A%22">Italiano A</searchLink>; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.; Bergonie Institut, CLCC, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Djabarouti+S%22">Djabarouti S</searchLink>; Department of Pharmacy, CHU Bordeaux, Pessac, France.; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Guyon+J%22">Guyon J</searchLink>; BRIC, UMR1312, Univ. Bordeaux, INSERM, Bordeaux, France.; Department of Medical Pharmacology, CHU Bordeaux, Bordeaux, France.; Department of Biochemistry, CHU Bordeaux, Bordeaux, France.
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