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Cathepsin S regulates antitumor immunity through autophagic degradation of PD-L1 in colorectal cancer cells.

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Title: Cathepsin S regulates antitumor immunity through autophagic degradation of PD-L1 in colorectal cancer cells.
Authors: Taheri Baghmisheh S; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan., Chen CH; Department of Mathematics, University of Taipei, Taipei, Taiwan., Yeh YM; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Lin PC; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Genomic Medicine, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Chen PC; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chan RH; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Kang JW; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Lee CT; Department of Pathology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Tsai HJ; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan., Fang YC; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan., Cheung CHA; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chang KY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chang JY; TMU Research Center of Cancer Translational Medicine, Taipei Cancer Center, Taipei Medical University Hospital, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan., Chen SH; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan. Bryanchen@nhri.edu.tw.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Bryanchen@nhri.edu.tw.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2025 Aug 12; Vol. 74 (9), pp. 287. Date of Electronic Publication: 2025 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cathepsin S regulates antitumor immunity through autophagic degradation of PD-L1 in colorectal cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Taheri+Baghmisheh+S%22">Taheri Baghmisheh S</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; Department of Mathematics, University of Taipei, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+YM%22">Yeh YM</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PC%22">Lin PC</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Genomic Medicine, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+PC%22">Chen PC</searchLink>; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chan+RH%22">Chan RH</searchLink>; Division of Colorectal Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kang+JW%22">Kang JW</searchLink>; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+CT%22">Lee CT</searchLink>; Department of Pathology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HJ%22">Tsai HJ</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fang+YC%22">Fang YC</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheung+CHA%22">Cheung CHA</searchLink>; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+KY%22">Chang KY</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+JY%22">Chang JY</searchLink>; TMU Research Center of Cancer Translational Medicine, Taipei Cancer Center, Taipei Medical University Hospital, College of Medicine, Taipei Medical University, Taipei, Taiwan.; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan. Bryanchen@nhri.edu.tw.; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Bryanchen@nhri.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2025 Aug 12; Vol. 74 (9), pp. 287. <i>Date of Electronic Publication: </i>2025 Aug 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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              Text: 2025 Aug 12
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