Substrate stiffness regulates triple-negative breast cancer signaling through CXCR4 receptor dynamics.

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Title: Substrate stiffness regulates triple-negative breast cancer signaling through CXCR4 receptor dynamics.
Authors: Ho KKY; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA., Buschhaus JM; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Zhang A; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA., Cutter AC; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA., Humphries BA; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA. brhu@med.umich.edu., Luker GD; Center for Molecular Imaging, Department of Radiology, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI, 48109, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Source: Scientific reports [Sci Rep] 2025 Aug 13; Vol. 15 (1), pp. 29621. Date of Electronic Publication: 2025 Aug 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-14495-x