Immunotherapy with lymphocytes derived from banked tumor tissue in two refractory NSCLC patients with leptomeningeal metastases: a report of two cases.

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Title: Immunotherapy with lymphocytes derived from banked tumor tissue in two refractory NSCLC patients with leptomeningeal metastases: a report of two cases.
Authors: Zheng AH; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Yu C; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Su YR; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China., Peng M; Department of Hospital Infection Management and Preventive Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Chen JY; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China., Wang FW; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Zhu XM; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Yan PY; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wang HT; Cancer Center, Department of Cardio-Thoracic Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Shen J; Cancer Center, Department of Cardio-Thoracic Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Chen WJ; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Li Q; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Chen Y; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Chen Y; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wang YS; Department of Ultrasound Medicine, the First Affiliated Hospital of Ningbo University, Ningbo, China., Gu HY; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Meng ZN; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China., Zhao JW; Department of Pathology, Jinhua Municipal Central Hospital, Jinhua, China., Ni WM; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wang TH; Cancer Center, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wu SL; Cancer Center, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Li M; Cancer Center, Gamma Knife Treatment Center, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wang Z; Cancer Center, Gamma Knife Treatment Center, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Cheng AP; Cancer Center, Department of Nuclear Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Huang XX; Cancer Center, Department of Hematology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Yang ZY; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Jiang JH; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wang QJ; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Qu J; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Zhang ST; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China., Shi KK; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Zhang HX; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Zhang DH; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China., Wu GQ; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
Source: Translational lung cancer research [Transl Lung Cancer Res] 2025 Jul 31; Vol. 14 (7), pp. 2880-2890. Date of Electronic Publication: 2025 Jul 28.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Pioneer Bioscience Publishing Company Country of Publication: China NLM ID: 101646875 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2218-6751 (Print) Linking ISSN: 22186751 NLM ISO Abbreviation: Transl Lung Cancer Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Immunotherapy with lymphocytes derived from banked tumor tissue in two refractory NSCLC patients with leptomeningeal metastases: a report of two cases.
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  Data: <searchLink fieldCode="AU" term="%22Zheng+AH%22">Zheng AH</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Su+YR%22">Su YR</searchLink>; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Peng+M%22">Peng M</searchLink>; Department of Hospital Infection Management and Preventive Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+FW%22">Wang FW</searchLink>; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhu+XM%22">Zhu XM</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yan+PY%22">Yan PY</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+HT%22">Wang HT</searchLink>; Cancer Center, Department of Cardio-Thoracic Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Shen+J%22">Shen J</searchLink>; Cancer Center, Department of Cardio-Thoracic Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+WJ%22">Chen WJ</searchLink>; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+YS%22">Wang YS</searchLink>; Department of Ultrasound Medicine, the First Affiliated Hospital of Ningbo University, Ningbo, China.<br /><searchLink fieldCode="AU" term="%22Gu+HY%22">Gu HY</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Meng+ZN%22">Meng ZN</searchLink>; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+JW%22">Zhao JW</searchLink>; Department of Pathology, Jinhua Municipal Central Hospital, Jinhua, China.<br /><searchLink fieldCode="AU" term="%22Ni+WM%22">Ni WM</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+TH%22">Wang TH</searchLink>; Cancer Center, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+SL%22">Wu SL</searchLink>; Cancer Center, Department of Neurosurgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Cancer Center, Gamma Knife Treatment Center, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Cancer Center, Gamma Knife Treatment Center, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cheng+AP%22">Cheng AP</searchLink>; Cancer Center, Department of Nuclear Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+XX%22">Huang XX</searchLink>; Cancer Center, Department of Hematology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+ZY%22">Yang ZY</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+JH%22">Jiang JH</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+QJ%22">Wang QJ</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Qu+J%22">Qu J</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+ST%22">Zhang ST</searchLink>; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Shi+KK%22">Shi KK</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+HX%22">Zhang HX</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+DH%22">Zhang DH</searchLink>; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+GQ%22">Wu GQ</searchLink>; Cancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.; Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101646875%22">Translational lung cancer research</searchLink> [Transl Lung Cancer Res] 2025 Jul 31; Vol. 14 (7), pp. 2880-2890. <i>Date of Electronic Publication: </i>2025 Jul 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pioneer+Bioscience+Publishing+Company%22">Pioneer Bioscience Publishing Company </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101646875 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2218-6751 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222186751%22">22186751 </searchLink><i>NLM ISO Abbreviation: </i>Transl Lung Cancer Res <i>Subsets: </i>PubMed not MEDLINE
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