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Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials.

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Title: Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials.
Authors: Rawat M; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Boonyalai N; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK., Smidt C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Luth MR; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Chen D; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA., Plater A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., Post J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., Lin; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., McMillan J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., Eadsforth T; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., Moliner-Cubel S; Global Health Medicines R&D, GSK, Severo Ochoa, 2, 28760 Tres Cantos, Spain., Billker O; Department of Molecular Biology, Umeå University, Sweden.; The Laboratory for Molecular Infection Medicine, Umeå University, Sweden., Rayner JC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK., Gamo FJ; Global Health Medicines R&D, GSK, Severo Ochoa, 2, 28760 Tres Cantos, Spain., Baragaña B; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK., Winzeler EA; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA., Lee MCS; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 06. Date of Electronic Publication: 2025 Aug 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Rawat+M%22">Rawat M</searchLink>; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Boonyalai+N%22">Boonyalai N</searchLink>; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Smidt+C%22">Smidt C</searchLink>; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.<br /><searchLink fieldCode="AU" term="%22Luth+MR%22">Luth MR</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Plater+A%22">Plater A</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Post+J%22">Post J</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Lin%22">Lin</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22McMillan+J%22">McMillan J</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Eadsforth+T%22">Eadsforth T</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Moliner-Cubel+S%22">Moliner-Cubel S</searchLink>; Global Health Medicines R&D, GSK, Severo Ochoa, 2, 28760 Tres Cantos, Spain.<br /><searchLink fieldCode="AU" term="%22Billker+O%22">Billker O</searchLink>; Department of Molecular Biology, Umeå University, Sweden.; The Laboratory for Molecular Infection Medicine, Umeå University, Sweden.<br /><searchLink fieldCode="AU" term="%22Rayner+JC%22">Rayner JC</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gamo+FJ%22">Gamo FJ</searchLink>; Global Health Medicines R&D, GSK, Severo Ochoa, 2, 28760 Tres Cantos, Spain.<br /><searchLink fieldCode="AU" term="%22Baragaña+B%22">Baragaña B</searchLink>; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Science, University of Dundee, Dundee, DD1 5EH, UK.<br /><searchLink fieldCode="AU" term="%22Winzeler+EA%22">Winzeler EA</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lee+MCS%22">Lee MCS</searchLink>; Division of Biological Chemistry and Drug Discovery, Wellcome Centre for Anti-Infectives Research, University of Dundee, Dundee, DD1 5EH, UK.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
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